NYPD Red is a special task force charged with protecting the interests of Manhattan's wealthiest and most powerful citizens. When a world-famous movie producer is poisoned on the first day of a Manhattan film festival called Hollywood on the Hudson, they are the first ones called. Then an actor is killed on the set of a film. And a Molotov cocktail explodes at a movie premiere.

NYPD Detective Michael Bennett is about to take on the most sinister challenge of his career. The nation has fallen into mourning after the unexpected death of a beloved former first lady, and the most powerful people in the world gather in New York for her funeral. Then the inconceivable occurs. Billionaires, politicians, and superstars of every kind are suddenly trapped within one man's brilliant and cold-blooded scenario.

Alex Cross is a homicide detective with a PhD in psychology. He works and lives in the ghettos of D. C. and looks like Muhammad Ali in his prime. He's a tough guy from a tough part of town who wears Harris Tweed jackets and likes to relax by banging out Gershwin tunes on his baby grand piano. But he also has two adorable kids of his own, and they are his own special vulnerabilities. Jezzie Flanagan is the first woman ever to hold the highly sensitive job as supervisor of the Secret Service in Washington.

For Hannah Shapiro, a beautiful young American student, this particular nightmare began eight years ago in Los Angeles, when Jack Morgan, owner of Private—the world's most exclusive detective agency—saved her from a horrific death. She has fled her country, but can't flee her past. The terror has followed her to London, and now it is down to former Royal Military Police Sergeant Dan Carter, head of Private London, to save her all over again.

Evan Smoak is a man with skills, resources, and a personal mission to help those with nowhere else to turn. He’s also a man with a dangerous past. Chosen as a child, he was raised and trained as an Orphan, an off-the-books black box program designed to create the perfect deniable intelligence asset: An assassin. Evan was Orphan X - until he broke with the program and used everything he learned to disappear. But now someone is on his tail.