He slips into their homes at night and walks silently into bedrooms where women lie sleeping, unaware of the horrors they soon will endure. The precision of the killer's methods suggests he is a deranged man of medicine, propelling the Boston newspapers and the frightened public to name him "The Surgeon". The cops' only clue rests with another surgeon, the victim of a nearly identical crime. Two years ago, Dr. Catherine Cordell fought back and killed her attacker before he could complete his assault.

It's June in Montreal, and Dr. Temperance Brennan, who has left a shaky marriage back home in North Carolina to take on the challenging assignment of Director of Forensic Anthropology for the province of Quebec, looks forward to a relaxing weekend in beautiful Quebec City. First, though, she must stop at a newly uncovered burial site in the heart of the city. The remains are probably old and only of archeological interest, but Tempe must make sure they're not a case for the police. One look at the decomposed and decapitated corpse, stored neatly in plastic bags, tells her she'll spend the weekend in the crime lab.

Former spy Maggie Bird came to the seaside village of Purity, Maine, eager to put the past behind her after a mission went tragically wrong. These days, she’s living quietly on her chicken farm, still wary of blowback from the events that forced her early retirement. But when a body turns up in Maggie’s driveway, she knows it’s a message from former foes who haven’t forgotten her. Maggie turns to her local circle of old friends—all retirees from the CIA—to help uncover the truth about who is trying to kill her, and why.

Recently engaged and deeply ensconced in her third year of surgical residency in Chicago, Emily Hartford gets a shock when she is called home to Freeport, Michigan, the small town she fled a decade ago after the death of her mother. Her estranged father, the local medical examiner, has had a massive heart attack. At the hospital, she finds her father in near total denial of the seriousness of his condition. He insists that the best thing Emily can do to help him is to take on the autopsy of a senator's teen daughter whose sudden, unexplained death has just rocked the sleepy town.

NYPD Detective Michael Bennett is about to take on the most sinister challenge of his career. The nation has fallen into mourning after the unexpected death of a beloved former first lady, and the most powerful people in the world gather in New York for her funeral. Then the inconceivable occurs. Billionaires, politicians, and superstars of every kind are suddenly trapped within one man's brilliant and cold-blooded scenario. Bennett, father of 10, is pulled into the fray.