Located off a desolate stretch of Interstate 50, Desperation, Nevada, has few connections with the rest of the world. It is a place, though, where the seams between worlds are thin. And it is a place where several travelers are abducted by Collie Entragian, the maniacal police officer of Desperation. Entragian uses various ploys for the abductions, from an arrest for drug possession to "rescuing" a family from a nonexistent gunman.

Lisey lost her husband, Scott, two years ago, after a 25-year marriage of profound and sometimes frightening intimacy. Scott was an award-winning, best-selling novelist and a very complicated man. Early in their relationship, before they married, Lisey knew there was a place Scott went - a place that both terrified and healed him, could eat him alive or give him the ideas he needed in order to live. Now it’s Lisey’s turn to face Scott’s demons, to go to that terrifying place known as Boo’ya Moon.

Even four years after the sudden death of his wife, best selling novelist Mike Noonan can't stop grieving, nor can he return to his writing. He moves into his isolated house by the lake, which becomes the site of ghostly visitations, ever-escalating nightmares, and the sudden recovery of his writing ability. What are the forces that have been unleashed here - and what do they want of Mike Noonan?

Charlie Reade looks like a regular high school kid, great at baseball and football, a decent student. But he carries a heavy load. His mom was killed in a hit-and-run accident when he was 10, and grief drove his dad to drink. Charlie learned how to take care of himself—and his dad. Then, when Charlie is 17, he meets a dog named Radar and his aging master, Howard Bowditch, a recluse in a big house at the top of a big hill, with a locked shed in the backyard. Sometimes strange sounds emerge from it.

Billy Summers is a man in a room with a gun. He’s a killer for hire and the best in the business. But he’ll do the job only if the target is a truly bad guy. And now Billy wants out. But first there is one last hit. Billy is among the best snipers in the world, a decorated Iraq war vet, a Houdini when it comes to vanishing after the job is done. So what could possibly go wrong?

In a small New England town, over half a century ago, a shadow falls over a small boy playing with his toy soldiers. Jamie Morton looks up to see a striking man, the new minister. Charles Jacobs, along with his beautiful wife, will transform the local church. The men and boys are all a bit in love with Mrs. Jacobs; the women and girls feel the same about Reverend Jacobs - including Jamie’s mother and beloved sister, Claire. With Jamie, the Reverend shares a deeper bond based on a secret obsession.

Johnny Smith awakens from a five-year coma after his car accident and discovers that he can see people's futures and pasts when he touches them. Many consider his talent a gift; Johnny feels cursed. His fiancée married another man during his coma, and people clamor for him to solve their problems. When Johnny has a disturbing vision after he shakes the hand of an ambitious and amoral politician, he must decide if he should take drastic action to change the future.

On an entirely normal, beautiful fall day in Chester's Mill, Maine, the town is inexplicably and suddenly sealed off from the rest of the world by an invisible force field. Planes crash into it and fall from the sky in flaming wreckage, a gardener's hand is severed as "the dome" comes down on it, people running errands in the neighboring town are divided from their families, and cars explode on impact. No one can fathom what this barrier is, where it came from, and when - or if - it will go away.

Leland Gaunt opens a new shop in Castle Rock called Needful Things. Anyone who enters his store finds the object of his or her lifelong dreams and desires: a prized baseball card, a healing amulet. In addition to a token payment, Gaunt requests that each person perform a little "deed", usually a seemingly innocent prank played on someone else from town. These practical jokes cascade out of control, and soon the entire town is doing battle with itself. Only Sheriff Alan Pangborn suspects that Gaunt is behind the population's increasingly violent behavior.

In the frigid pre-dawn hours, in a distressed Midwestern city, hundreds of desperate unemployed folks are lined up for a spot at a job fair. Without warning, a lone driver plows through the crowd in a stolen Mercedes, running over the innocent, backing up, and charging again. Eight people are killed; fifteen are wounded. The killer escapes. Mr. Mercedes is a war between good and evil, from the master of suspense whose insight into the mind of this obsessed, insane killer is chilling and unforgettable.

Rosie Daniels leaves her husband, Norman, after 14 years in an abusive marriage. She is determined to lose herself in a place where he won't find her. She'll worry about all the rest later. Alone in a strange city, she begins to make a new life, and good things finally start to happen. Meeting Bill is one, and getting an apartment is another. Still, it's hard for Rosie not to keep looking over her shoulder, and with good reason. Norman is a cop, with the instincts of a predator.

In the middle of the night, in a house on a quiet street in suburban Minneapolis, intruders silently murder Luke Ellis' parents and load him into a black SUV. The operation takes less than two minutes. Luke will wake up at The Institute, in a room that looks just like his own, except there's no window. And outside his door are other doors, behind which are other kids with special talents - telekinesis and telepathy - who got to this place the same way Luke did: Kalisha, Nick, George, Iris, and 10-year-old Avery Dixon.

An 11-year-old boy's violated corpse is found in a town park. Eyewitnesses and fingerprints point unmistakably to one of Flint City's most popular citizens. He is Terry Maitland, Little League coach, English teacher, husband, and father of two girls. Detective Ralph Anderson, whose son Maitland once coached, orders a quick and very public arrest. Maitland has an alibi, but Anderson and the district attorney soon add DNA evidence to go with the fingerprints and witnesses. Their case seems ironclad.

Thad Beaumont would like to say he is innocent. He'd like to say he has nothing to do with the twisted imagination that produced his best-selling novels. He'd like to say he has nothing to do with the series of monstrous murders that keep coming closer to his home. But how can Thad deny the ultimate embodiment of evil that goes by the name he gave it - and signs its crimes with Thad's bloody fingerprints?

Writer Bobbi Anderson becomes obsessed with digging up something she's found buried in the woods near her home. With the help of her friend, Jim Gardener, she uncovers an alien spaceship. Though exposure to the Tommyknockers, who piloted the alien ship, has harmful effects on residents' health, the people of Haven develop a talent for creating innovative devices under their increasingly malignant influence.