People start dropping dead around Charlie, giant ravens perch on his building, and it seems that everywhere he goes, a dark presence whispers to him from under the streets. Strange names start appearing on his nightstand notepad, and before he knows it, those people end up dead, too. Yup, it seems that Charlie Asher has been recruited for a new job, an unpleasant but utterly necessary one: Death.

San Francisco, 1947. Bartender Sammy “Two Toes” Tiffin and the rest of the Cookie’s Coffee Irregulars—a ragtag bunch of working mugs last seen in Noir—are on the hustle: they’re trying to open a driving school; shanghai an abusive Swedish stevedore; get Mable, the local madam, and her girls to a Christmas party at the State Hospital without alerting the overzealous head of the S.F.P.D. vice squad.

It's not every afternoon that an enigmatic, comely blonde named Stilton (like the cheese) walks into the scruffy gin joint where Sammy "Two Toes" Tiffin tends bar. It's love at first sight, but before Sammy can make his move, an air force general named Remy arrives with some urgent business. 'Cause when you need something done, Sammy is the guy to go to; he's got the connections on the street.

A striking red-head, 20-something Jody is attacked and transformed into a vampire while walking home one night in downtown San Francisco. Befriending 19-year-old Tommy, Jody tries to understand her new undead life, but trouble finds her when the cops start suspecting Tommy of being a local bloodsucking serial killer.

In Christopher Moore's ingenious debut novel, we meet one of the most memorably mismatched pairs in the annals of literature. The good-looking one is one-hundred-year-old ex-seminarian and "roads" scholar Travis O'Hearn. The green one is Catch, a demon with a nasty habit of eating most of the people he meets.