On the day she was abducted, Annie O’Sullivan, a 32-year-old Realtor, had three goals: sell a house, forget about a recent argument with her mother, and be on time for dinner with her ever-patient boyfriend. The open house is slow, but when her last visitor pulls up in a van as she’s about to leave, Annie thinks it just might be her lucky day after all.

In the lockdown ward of a psychiatric hospital, Dr. Nadine Lavoie is in her element. She has the tools to help people, and she has the desire: Healing broken families is what she lives for. But Nadine doesn’t want to look too closely at her own past because there are whole chunks of her life that are black holes. It takes all her willpower to tamp down her recurrent claustrophobia, and her daughter, Lisa, is a runaway who has been on the streets for seven years. When a distraught woman, Heather Simeon, is brought into the Psychiatric Intensive Care Unit after a suicide attempt, Nadine gently coaxes her story out of her - and learns of some troubling parallels to her own life.

The Cold Creek Highway stretches close to five hundred miles through British Columbia’s rugged wilderness to the west coast. Isolated and vast, it has become a prime hunting ground for predators. For decades, young women traveling the road have gone missing. Motorists and hitchhikers, those passing through or living in one of the small towns scattered along the region, have fallen prey time and again. And no killer or abductor who has stalked the highway has ever been brought to justice.

Eleven years ago, Lindsey Nash escaped into the night with her young daughter and left an abusive relationship. Her ex-husband, Andrew, was sent to jail and Lindsey started over with a new life. Now, Lindsey is older and wiser, with her own business and a teenage daughter who needs her more than ever. When Andrew is finally released from prison, Lindsey believes she has cut all ties and left the past behind her. But she gets the sense that someone is watching her, tracking her every move.

Toni Murphy was eighteen when she and her boyfriend, Ryan, were wrongly convicted of the murder of her younger sister. Now she is thirty-four and back in her hometown, working every day to forge and adjust to a new life on the outside. She's doing everything in her power to avoid violating her parole and going back to prison. But nothing is making that easy – not Ryan, who is convinced he can figure out the truth; not her mother, who clearly doubts Toni's innocence; and certainly not the group of women who made Toni's life miserable in high school.