Everyone knows everyone in the tiny town of Bourne, but the Mitchell triplets are especially beloved. Mirabel is the smartest person anyone knows, and no one doubts it just because she can’t speak. Monday is the town’s purveyor of books now that the library’s closed - tell her the book you think you want, and she’ll pull the one you actually do from the microwave or her sock drawer. Mab’s job is hardest of all: get good grades, get into college, get out of Bourne.

It’s February 1976, and Odessa, Texas, stands on the cusp of the next great oil boom. While the town’s men embrace the coming prosperity, its women intimately know and fear the violence that always seems to follow. In the early hours of the morning after Valentine’s Day, 14-year-old Gloria Ramírez appears on the front porch of Mary Rose Whitehead’s ranch house, broken and barely alive. The teenager had been viciously attacked in a nearby oil field - an act of brutality that is tried in the churches and barrooms of Odessa before it can reach a court of law.

Chemist Elizabeth Zott is not your average woman. In fact, Elizabeth Zott would be the first to point out that there is no such thing as an average woman. But it’s the early 1960s and her all-male team at Hastings Research Institute takes a very unscientific view of equality. Except for one: Calvin Evans; the lonely, brilliant, Nobel–prize nominated grudge-holder who falls in love with—of all things—her mind. True chemistry results.

He was the first person to inspire her, to move her, to truly understand her. Was he meant to be the last? Lucy is faced with a life-altering choice. But before she can make her decision, she must start her story - their story - at the very beginning. Lucy and Gabe meet as seniors at Columbia University on a day that changes both of their lives forever. Together, they decide they want their lives to mean something, to matter. When they meet again a year later, it seems fated - perhaps they'll find life's meaning in each other.

Olivia McAfee knows what it feels like to start over. Her picture-perfect life—living in Boston, married to a brilliant cardiothoracic surgeon, raising their beautiful son, Asher—was upended when her husband revealed a darker side. She never imagined that she would end up back in her sleepy New Hampshire hometown, living in the house she grew up in and taking over her father’s beekeeping business. Lily Campanello is familiar with do-overs, too. When she and her mom relocate to Adams, New Hampshire, for her final year of high school, they both hope it will be a fresh start.

William Waters grew up in a house silenced by tragedy, where his parents could hardly bear to look at him, much less love him—so when he meets the spirited and ambitious Julia Padavano in his freshman year of college, it’s as if the world has lit up around him. With Julia comes her family, as she and her three sisters are inseparable: Sylvie, the family’s dreamer, is happiest with her nose in a book; Cecelia is a free-spirited artist; and Emeline patiently takes care of them all.

Emmeline lives on a remote island with her father, who teaches her about the natural world through her senses. What he won’t explain are the mysterious scents stored in glass bottles that line the walls of their cabin, or the origin of the machine that creates them. As Emmeline grows, however, so too does her curiosity, until one day the unforeseen happens, and Emmeline is vaulted out into the real world—a place of love, betrayal, ambition, and revenge. To understand her past, Emmeline must unlock the clues to her identity.

California, 1938—When she loses her parents in an accident, sixteen-year-old Rosanne is taken in by the owners of the vineyard where she has lived her whole life as the vinedresser’s daughter. She moves into Celine and Truman Calvert’s spacious house with a secret, however—Rosie sees colors when she hears sound. She promised her mother she’d never reveal her little-understood ability to anyone, but the weight of her isolation and grief prove too much for her. Driven by her loneliness she not only breaks the vow to her mother, but in a desperate moment lets down her guard and ends up pregnant.

Esme is born into a world of words. Motherless and irrepressibly curious, she spends her childhood in the Scriptorium, an Oxford garden shed in which her father and a team of dedicated lexicographers are collecting words for the very first Oxford English Dictionary. Young Esme’s place is beneath the sorting table, unseen and unheard. One day a slip of paper containing the word bondmaid flutters beneath the table. She rescues the slip and, learning that the word means “slave girl,” begins to collect other words discarded or neglected by the dictionary men.

Maya was a high school senior when her best friend, Aubrey, dropped dead in front of the enigmatic man named Frank whom they’d been spending time with all summer. Seven years later, Maya lives in Boston with a loving boyfriend and is kicking the secret addiction that has allowed her to cope with what happened years ago, the gaps in her memories, and the lost time that she can’t account for. But her past comes rushing back when she comes across a recent YouTube video in which a young woman suddenly keels over and dies in a diner while sitting across from none other than Frank.