Andrea Sachs, a small-town girl fresh out of college, is hired as the assistant to Miranda Priestly, the successful editor of Runway magazine. Andrea finds herself in an office that shouts Prada! Armani! Versace! at every turn. As things escalate from the merely unacceptable to the downright outrageous, Andrea begins to realize that the job a million girls would die for may just kill her. And even if she survives, she has to decide whether the job is worth the price of her soul.

Charlotte "Charlie" Silver has always been a good girl. She excelled at tennis early, coached by her father, a former player himself, and soon became one of the top juniors in the world. When she leaves UCLA - and breaks her boyfriend's heart - to turn pro, Charlie joins the world's best athletes, who travel 11 months a year, competing without mercy for Grand Slam titles and Page Six headlines.

When 27-year-old Bette Robinson quits her Manhattan banking job, she knows she won't miss the 80-hour workweeks, her claustrophobic cubicle or her revolting boss's Quotes of the Day. Then Bette meets Kelly, head of Manhattan's hottest PR and events planning firm, and suddenly she has a brand-new job where the primary requirement is to see and be seen. The work at Kelly & Company takes Bette inside the VIP rooms of the city's most exclusive nightclubs, to parties crowded with celebrities and socialites.

Leigh, Adriana and Emmy are best friends, all leading different lives and about to make some extreme choices. The three girls meet for dinner one evening and make a pact - they each have to change one thing in their lives by the end of the year.

Brooke was drawn to the soulful, enigmatic Julian Alter the very first time she heard him perform “Hallelujah” at a dark East Village dive bar. Now five years married, Brooke balances two jobs—as a nutritionist at NYU Hospital and as a consultant to an Upper East Side girls’ school, where privilege gone wrong and disordered eating run rampant—in order to help support her husband’s dream of making it in the music world.