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The Tylenol Murders: How One Bottle Changed America Forever

The Tylenol Murders: How One Bottle Changed America Forever

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In 1982, seven people in the Chicago area died after taking Tylenol—each capsule laced with deadly cyanide. The case sparked national panic, triggered sweeping changes in packaging laws, and remains unsolved to this day.

In this episode, Caleb is joined by his brother Josh and their dad, Papa Jefe, to unpack the chilling details of the Tylenol Murders. Along the way, they reflect on growing up in the 80s, the rise of tamper-proof packaging, and how this case still echoes today.

⏱️ Timestamps:

00:00 – Intro + What Happened in 1982

00:30 – The Tragedy Begins: Mary Kellerman & the Janus Family

02:08 – Panic, Recall, and Nationwide Fear

03:47 – The Mysterious Extortion Letter

05:49 – What Packaging Was Like Before 1982

11:53 – Ronald Clark O’Brien and the Pixy Stix Poisoning

14:34 – The FDA’s Delayed Response

25:45 – Why Crimes Were Harder to Solve in the 80s

34:05 – Why the Prime Suspect Walked Free

44:00 – Final Thoughts + Protecting Your Family

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