Biological Technology

In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading. Coming at a time of economic recession and declining technological competitiveness in the United States, the event ignited a period of speculative frenzy over biotechnology.

The discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Howard Markel skillfully recreates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin - fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s - who becomes a focal point for Markel.

Elisabeth Tova Bailey tells the intimate and inspiring story of her year-long encounter with a snail. While an illness keeps her bedridden, she becomes an astute and amused observer of the snail's surprising nocturnal adventures as it lives in a flowerpot on her nightstand. Intrigued by the snail’s clear decision making abilities, hydraulic locomotion, mysterious courtship, and molluscan anatomy, Bailey takes the listener deep into the life of this tiny amazing animal. With wit and grace, The Sound of a Wild Snail Eating recounts a remarkable journey of human and gastropod survival and resilience, and shows how the natural world illuminates our own human existence. Winner of the William Saroyan International Prize for Nonfiction, the John Burrough Medal Award for Natural History, and a National Outdoor Book Award. If you enjoyed Wesley the Owl, The Guest Cat, and Marley & Me, you'll enjoy this unique interspecies audiobook listen.

North America's biggest cat was once killed for bounty dollars, slaughtered with impunity and driven toward extinction. But today's cat of intrigue, despite our lingering fears and misconceptions, has returned to much of its native range in the western United States and gained respect as a predator integral and necessary to wild ecosystems. This turnaround was triggered by one man: Maurice Hornocker. Cougars on the Cliff recounts the early years of his research when he tracked lions following a dog's nose and footprints in the snow—before telemetry was available.

From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic engineering is shaking the core foundations of our lives-sex, war, love, and death. At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.

This science classic by Paul de Kruif chronicles the pioneering bacteriological work of the first scientists to see and learn from the microscopic world. Paul de Kruif's Microbe Hunters is a timeless dramatization of the scientists, bacteriologists, doctors, and medical technicians who discovered microbes and invented the vaccines to counter them.

The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic medication. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.

The natural world teems with remarkable conversations, many beyond human hearing range. Scientists are using groundbreaking digital technologies to uncover these astonishing sounds, revealing vibrant communication among our fellow creatures across the Tree of Life. At once meditative and scientific, The Sounds of Life shares fascinating and surprising stories of nonhuman sound, interweaving insights from technological innovation and traditional knowledge.

When neuroscientist Susan Barry was 50 years old, she took an unforgettable trip to Manhattan. As she emerged from the dim light of the subway into the sunshine, she saw a view of the city that she had witnessed many times in the past but now saw in an astonishingly new way. Skyscrapers on street corners appeared to loom out toward her like the bows of giant ships. Tree branches projected upward and outward, enclosing and commanding palpable volumes of space.

A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

The name of Charles Darwin is known to nearly all who have had the benefit of a Western-style education. It is synonymous with the theory of evolution and due to his perspective of man as an animal, his worked ushered in a new paradigm of understanding of the physical and mental behavior of man. However, because of the immense impact of his best known theory, most know only of his work through reviews and historical reports.

From one of the world’s leading data scientists, a landmark tour ofthe new science of idea flow, offering revolutionary insights into the mysteries of collective intelligence and social influence.

In September 1838, a young Englishman named Charles Darwin hit upon the idea that "natural selection" among competing individuals would lead to wondrous adaptations and species diversity. Twenty-one years passed between that epiphany and publication of On the Origin of Species. The human drama and scientific controversy of that time constitute a fascinating, tangled tale that illuminates this cautious naturalist who sparked an intellectual revolution.

Jailed as a scapegoat for Stalin's famines, Vavilov had traveled over five continents, collected hundreds of thousands of seeds in an effort to outline the ancient centers of agricultural diversity. Gary Paul Nabhan weaves together Vavilov's story with his own expeditions to Earth's richest agricultural landscapes and the cultures that tend them.

Charles Darwin's foremost biographer, Janet Browne, delivers a vivid and accessible introduction to the book that permanently altered our understanding of what it is to be human. A sensation on its publication in 1859, The Origin of the Species profoundly shocked Victorian readers by calling into question the belief in a Creator with its description of evolution through natural selection. And Darwin's seminal work is nearly as controversial today.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.

In The Plant Hunter, Dr. Quave weaves together science, botany, and memoir to tell us the extraordinary story of her own journey. Traveling by canoe, ATV, mule, airboat, and on foot, she has conducted field research in the flooded forests of the remote Amazon, the murky swamps of southern Florida, the rolling hills of central Italy, isolated mountaintops in Albania and Kosovo, and volcanic isles arising out of the Mediterranean - all in search of natural compounds, long-known to traditional healers, that could help save us all from the looming crisis of untreatable superbugs.

Charles Darwin did not deliberately set out to be the destroyer of mythical beliefs,” some of which, in his early days as a young Christian, he had previously espoused. He was a modest man who liked to avoid controversy of any kind, yet paradoxically, he was to be the cause of the greatest controversy in the history of science and religion.When Darwin embarked on the HMS Beagle in late December 1831, bound for the southern hemisphere, he could not have imagined that the experience would lead him to formulate a theory that would totally revolutionize the way in which we viewed the natural world.

Growing up in California, J. Craig Venter didn't appear to have much of a future. An unremarkable student, he nearly flunked out of high school. After being drafted into the army, he enlisted in the Navy and went to Vietnam, where the life-and-death struggles he encountered as a medic piqued his interest in science and medicine. After pursuing his advanced degrees, Venter quickly established himself as a brilliant and outspoken scientist.