Medical Diseases

It begins with numbness on her left leg. Then it spreads. Even though an MRI finds a "mass" on her brainstem, it takes two more years for Meredith O'Brien to learn what is causing that numbness. Months after her sixty-five-year-old mother dies from a fast-moving cancer, weeks after her father is hospitalized and she experiences an unexpected job change, she learns she has multiple sclerosis. Suddenly, Meredith, a married mother of three teens, has to figure out how to move forward into a life she no longer recognizes.

Drug overdoses are now the leading cause of death for Americans un­der the age of 50, claiming more lives than the AIDS epidemic did at its peak. Opioid abuse accounts for two-thirds of these overdoses, with over 100 Americans dying from opioid overdoses every day. Now Overcoming Opioid Addiction provides a comprehensive medical guide for opioid use disorder (OUD) sufferers, their loved ones, clinicians, and other professionals. Here is expertly presented, urgently needed in­formation and guidance

Backbone is a life-fulfilling message about managing chronic pain and living a life of purpose. For two decades, Karen Duffy, New York Times bestselling author, former MTV VJ, Revlon model, and actress, has managed to live an enriching life despite living in a state of constant pain. In this powerful, inspirational, funny, and important manual for surviving pain, Duffy draws on her experience as a patient advocate, trained recreational therapist, and hospice chaplain to illuminate gratifying methods people can use to cope with chronic pain.

The Headache Godfather traces the life of Seymour Diamond, MD, who was born in 1925, the son of Jewish immigrants from Ukraine and Slovakia, in Chicago, Illinois. Dr. Diamond revolutionized the practice of headache as a medical specialty when he opened the United States' first private headache practice, the Diamond Headache Clinic, in 1974. It quickly became a headache haven for sufferers from around the world.

Julie Flygare was on an ambitious path to success, entering law school at age 22, when narcolepsy destroyed the neurological boundaries between dreaming and reality in her brain. She faced terrifying hallucinations, paralysis, and excruciating sleepiness, aspects of dream sleep taking place while wide awake. Yet, narcolepsy was a wake-up call for Julie. Her illness propelled her onto a journey she never imagined, from lying paralyzed on her apartment floor to dancing euphorically at a nightclub; from the classrooms of Harvard Medical School to the start line of the Boston Marathon.

In this highly personal account, Dr Gibbs documents the effect his diagnosis has had on his life and explains his advocacy for improving early recognition of Alzheimer’s. Weaving clinical knowledge from decades caring for dementia patients with his personal experience of the disease, this is an optimistic tale of one man’s journey with early-stage Alzheimer’s disease.

Diagnosed as severely autistic at the age of three, Tito, nearly nonverbal, was brought up by his loving mother Soma, who taught him to read English and challenged him to write his own stories. The initial result was The Mind Tree, published in 2003, which Tito wrote between the ages of eight and 11. The Gold of the Sunbeams is an equally impressive, beautiful collection of stories, each prefaced by a charming note from Tito explaining how the story came into being.

Promising treatments now in more than 35,000 clinical trials could have dramatic impacts on cancer, autoimmune diseases, organ replacement, heart disease, and even aging itself. These treatments, which are saving the lives of patients in the trials, will soon be rolled to the medical community at large. The key to these breakthroughs is the use of living cells as medicine instead of traditional drugs. Research has found that our bodies are virtual treasure troves of adult cells that act as agents of remarkable healing and repair.

Over the last decade, scientists have discovered the importance and widespread presence in the body of a remarkable family of proteins known as prion proteins. Research links various types of prion proteins to neurodegenerative diseases such as Parkinson's and Alzheimer's—and this has fueled the search for new drugs that could halt the progression of these terrible disorders. Other discoveries have revealed the essential roles prion proteins play in memory and immunity, and the part they may have played in the beginnings of life on our planet.

An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.

Unearth the secrets to hormonal harmony, even if struggling with hormonal imbalance has been sending you on an emotional roller coaster for years. Are you tired of feeling like a stranger in your own body? Are irregular periods, mood swings, hot flashes, chronic fatigue, weight gain, or other confounding symptoms making your daily life a battle? Do you find yourself longing for the days of hormonal harmony, where you feel empowered and in control of your body? You are not alone.

In 1940s and ’50s America, polio is as dreaded as the atomic bomb. No one’s life is untouched by this disease that kills or paralyzes its victims, particularly children. Outbreaks of the virus across the country regularly put American cities in lockdown. Some of the world’s best minds are engaged in the race to find a vaccine. The man who succeeds will be a god.

The controversial Emanuel Revici, M.D., made the bones grow back in cancer patients, and restored health to AIDS patients as well as drug addicts and alcoholics. His medicines lifted debilitating migraines in as little as three minutes. Revici's reward? He was attacked and ostracized by the best. JAMA published false reports about his work. The American Cancer Society blasted him time and again. Meanwhile, word of mouth brought new patients to see him for decades.

Patti M. Hall’s life is pitched into an abyss of uncertainty when a golf ball-sized tumour is discovered in her teenage son’s head and he is diagnosed with gigantism, a disease of both legend and stigma. After scrambling to access a handful of medical experts in the field, Patti learns that her son could grow uncontrollably, his mobility could be permanently limited, and his life could be cut short without timely and aggressive treatment. Patti’s attention shifts fully to her son, away from her relationships as well as her own career and health.

For listeners touched by Paul Kalanithi’s When Breath Becomes Air and anyone with a life-threatening illness seeking healing of body, mind, and spirit, a fellow patient shares her journey of choosing to have the best day of her life by working as though she will live and living every moment as though she might die. Waking to the stunning realization she had cancer, Jocelyn Rasmussen’s first thought was that she needed a miracle. Her second thought was that she didn’t want to die with any unspent love or grace inside her.

Acclaimed CBS News reporter Barry Petersen writes about hearing the unimaginable; what it meant, what it still means, what he did---and didn't do---and how this beautiful love story needs to be heard by the thousands of families who have already heard that same devastating diagnosis: early onset Alzheimer's disease. Even though Barry has spent his long-time, award-winning television career covering wars and events that shaped the world, he was not even slightly prepared for what happened to his darling wife, Jan, and how it would impact his life.

When her husband, Alan, is injured in a speedboat accident, Cathy Crimmins reluctantly assumes the role of caregiver and learns to cope with the person he has become. No longer the man who loved obscure Japanese cinema and wry humor, Crimmins’ husband has emerged from the accident a childlike and unpredictable replica of his former self with a short attention span and a penchant for inane cartoons. Where Is the Mango Princess? is a breathtaking account that explores the very nature of personality - and the complexities of the heart.

“Strokes are the third-leading cause of death in America, and for the ‘lucky’ stroke victims who don’t die, about half will spend the rest of their lives trying to recover.” Roughly 700,000 American suffer a stroke each year and around 140,000 of them are fatal. Different Strokes is an in-depth look at what surviving, or not surviving, a stroke can mean.

In medical school, Paul Farmer found his life’s calling: To cure infectious diseases and to bring the lifesaving tools of modern medicine to those who need them most. Tracy Kidder’s magnificent account shows how one person can make a difference in solving global health problems through a clear-eyed understanding of the interaction of politics, wealth, social systems, and disease.

We have lost the war on cancer. We spend $150 billion each year treating it, yet - a few innovations notwithstanding - a patient with cancer is as likely to die of it as one was 50 years ago. Most new drugs add mere months to one's life at agonizing physical and financial cost. In The First Cell, Azra Raza offers a searing account of how both medicine and our society (mis)treats cancer, how we can do better, and why we must.