For 30 years, a secret agency called the Southern Reach has monitored expeditions into Area X - a remote and mysterious place that's sequestered from civilization. After the twelfth expedition, the Southern Reach is in disarray, and John Rodriguez (a.k.a. "Control") is the team's newly appointed head. From a series of interrogations, a cache of hidden notes, and more than 200 hours of profoundly troubling video footage, the secrets of Area X begin to reveal themselves - and what they expose pushes Control to confront truths about both himself and the agency he's promised to serve.

Before Area X, there was Ambergris. Jeff VanderMeer conceived what would become his first cult classic series of speculative works: the Ambergris trilogy. Now, for the first time ever, the story of the sprawling metropolis of Ambergris is collected into a single volume, including City of Saints and Madmen, Shriek: An Afterword, and Finch.

Area X has been cut off from the rest of the continent for decades. Nature has reclaimed the last vestiges of human civilization. This is the 12th expedition, and their group is made up of four women. Part of their mission is to map the terrain and collect specimens, and, above all, to avoid being contaminated by Area X itself. They arrive expecting the unexpected, and Area X delivers, but it's the surprises that came across the border with them, and the secrets the expedition members are keeping from one another, that change everything.  

It is winter in Area X, the mysterious wilderness that has defied explanation for 30 years, rebuffing expedition after expedition, refusing to reveal its secrets. As Area X expands, the agency tasked with investigating and overseeing it - the Southern Reach - has collapsed on itself in confusion. Now one last, desperate team crosses the border, determined to reach a remote island that may hold the answers they've been seeking. 

Security consultant “Jane Smith” receives an envelope with a key to a storage unit that holds a taxidermied hummingbird and clues leading her to a taxidermied salamander. Silvina, the dead woman who left the note, is a reputed ecoterrorist and the daughter of an Argentine industrialist. By taking the hummingbird from the storage unit, Jane sets in motion a series of events that quickly spin beyond her control.