Ellie Fisher loves most things about being a nurse in the emergency department . . . just not working with Regina Novak, an icy attending physician who acts as if she's God's gift to medicine. The dislike is completely mutual. Regina thinks Ellie is a starry-eyed romantic with a sentimental attitude that has no place at work. When Regina gets talked into volunteering at a singles auction, Ellie accidentally bids on her—and ends up winning. Oops! Since the money raised is for a good cause, they reluctantly decide to go through with the dates.

Born and raised in St. Claire, Lindsay Juneau's life was seemingly full raising a six-year-old daughter and caring for her widowed mother. Of course, things aren't always what they seem, and the newest resident of St. Claire isn't buying the ruse. Veterinarian Nicole Allen is looking for something different. She finds it in St. Claire with its hypochondriac rabbits, shotgun-toting shut-ins, and eclectic mix of people. The most alluring, though, is a woman who's also looking for something different.

Taryn Louden has inherited her father's family home and more money than she ever thought she'd see in a lifetime. There are just a few problems with it all. The house is expensive to maintain, local kids entertain themselves by pulling pranks on her, and there might be a few departed Loudens still hanging around. The only real bonus is the sexy contractor Taryn's aunt hired to restore the Louden family home back to its former glory.

When Shawna Haydel was 16 years old, she dropped Ashton Guidry's name into a potion that would supposedly make Ashton fall in love with her. She knew it was silly, but she clung to one irrational thread of hope their friend Patty's concoction would grant her heart's desire. Shawna's hopes were dashed when Ashton packed up her things and went away to college completely unaware of Shawna's feelings. Twenty-three years after Patty's potion was brewed, Ashton returns to her hometown. She finds time has changed a lot, including Shawna.

Kellen McLin has been waiting for her moment for a long time. She says when two people who are meant to be together find each other, they know it instantly. Kellen believes her moment girl has finally arrived, but there's one big problem - she's a Sealy. The McLins and the Sealys are South Louisiana's version of the Hatfields and the McCoys.