Since childhood Nila Carter has been made to spend every weekend at the family cabin. In her teenage years she believes it to be a prison; as an adult it becomes her sanctuary and means to survive. When a mysterious outbreak occurs in India, Nila's brother, Bobby, a virologist with the CDC, places the family on a precautionary alert to be ready to bug out. Unlike anything he's ever seen, the rabies-like virus is not just deadly; it causes extreme violent behavior in those infected.

Cassie Forrest isn't surprised to learn that the day she’s decided to get her life together is also the day the world ends. After all, she’s been on a self-imposed losing streak since her survivalist parents died: she’s stopped painting, broken off her engagement to Adrian and dated a real jerk. Rectifying her mistakes has to wait, however, because Cassie and her friends have just enough time to escape Brooklyn for her parents’ cabin before Bornavirus LX turns them into zombies, too.

The morning that the world ends, Katie is getting ready for court and housewife Jenni is taking care of her family. Less than two hours later, they are fleeing for their lives from a zombie horde. Thrown together by circumstance, Jenni and Katie become a powerful zombie-killing partnership, mowing down zombies as they rescue Jenni's stepson, Jason, from an infected campground.

Rose Winter has enough problems. With a marriage going down the tubes and a dreaded anniversary party on the horizon, the last thing she needs is the zombie apocalypse. She wanted to get drunk and sing karaoke, not murder her undead neighbors. It’s clear the party’s over, however, now Rose has more problems - a missing husband, an overbearing houseguest, and keeping her family alive.

A survivor of undead suburbia, mountain man Augustus “Gus” Berry is extremely careful when it comes to his actions and movements. He takes no chances and painstakingly weighs every decision—until he sets out for the hospital at the edge of town, hoping to discover a treasure trove of essential supplies. Soon, Gus will experience terror the likes of which he's never encountered before . . .