The Great Devourer is descending on the world of Tarsis Ultra, but to defeat the xenos horrors, Captain Uriel Ventris may have to embark upon a dangerous and unorthodox mission.

Supreme Grand Master Azrael summons Lazarus and his Fifth Company to honour an old debt on the Knight world of Reis – a planet upon which the warp has set its hungry gaze. But Lazarus is not so sure Reis wants to be saved – its Knights are long lost, its governance is dogged by political strife, and internecine conflict hampers the world’s defence against an ancient evil. ­An evil which, like Lazarus himself, refuses to die.

Faced with an ork invasion of Piscina IV, the 3rd Company of the Dark Angels believes the threat to be minimal. As enemy numbers continue to increase, their commander, Captain Belial, insists that his Company are strong enough to resist. But Scout-Sergeant Naaman knows just how dangerous this foe can be, and when a renewed offensive takes the Dark Angels by surprise, the orks swarm towards Kadillus Harbour.

Uriel Ventris, newly ascended to the ranks of the Primaris, leads warriors of the Fourth Company from the Indomitus Crusade of Roboute Guilliman to a world on the frontiers of Ultramar. Once a battleground against the orks, Sycorax is now under furious assault from an enemy of ancient times – the necrons. The Ultramarines have faced these baleful xenos before, but Uriel senses the hand of a foe from his past at work on Sycorax, a tally unfinished and a debt to the Imperium finally come due.

On the grim death world of Fenris, the Space Wolves Chapter selects its aspirants from the best and brightest of the young tribesmen. Ragnar of the Thunderfist tribe finds his life changed forever when he is chosen. After being revived from a savage death on the battlefield, Ragnar is recruited into the fearsome Space Wolves Chapter. He is then thrown into a galactic war against the dark forces of Chaos. However, the implanting of the Canis Helix unleashes his primal instincts and Ragnar must fight to control the beast within him.

The primarch Roboute Guilliman of the Ultramarines has returned in the galaxy’s hour of need, and all muster to his Indomitus Crusade to hold back the darkness. Amongst these heroes is Cato Sicarius, Master of the Watch and vaunted captain of Second Company. Disaster befalls Sicarius and his brave warriors as their ship, the Emperor’s Will, is lost to the hellish warp, its entire crew believed slain. But Sicarius endures, though he and his men are fighting for their very survival against the denizens of the Great Rift - the daemons and renegades of Chaos.

The scattered worlds of the Elara's Veil nebula were once protected by the oath of unity sworn by three mighty Chapters of the Adeptus Astartes. The Star Scorpions were undone by flaws in their genetic coding. The Celestial Lions were ravaged by the Inquisition for sins they did not commit. Now, after hundreds of years, only the Emperor's Spears still keep their vigil. They are barbarian watchmen against the Outer Dark, bloodied but unbroken in their long duty.

The fortress world of Regium has a proud history, For millennia, it has endured when others have fallen to ruin and damnation, standing defiant in defence of the Imperium of Man. But now it is shaken. Parasitic plagues run rampant, and Regium's citizens are haunted by dreams of horrific monsters feasting upon their flesh and marrow. Lieutenant Castamon of the Ultramarines recognises these signs of an impending Tyranid invasion all too well. Rallying his warriors, the battle-hardened veteran launches a strike force to slaughter the xenos in the outer system, before it can reach Regium.

The Blood Angels Chapter of Space Marines is under threat. Having obliterated all human life in the Red Scar region of space, the largest tendril of Hivefleet Leviathan ever seen in the Imperium has converged and is making relentlessly for Baal. To face this awesome foe, Commander Dante has called upon the Successor Chapters of the ancient Ninth Legion. The Sons of Sanguinius gather in numbers not seen since the dark days of the Horus Heresy.

After seven years of bitter war, the end has come at last for the conflict known infamously as the Horus Heresy. Terra now lies within the Warmaster’s sights, the Throneworld and the seat of his father’s rule. Horus’ desire is nothing less than the death of the Emperor of Mankind and the utter subjugation of the Imperium. He has become the ascendant vessel of Chaos and amassed a terrible army with which to enact his will and vengeance. But the way to the Throne will be hard as the primarch Rogal Dorn, the Praetorian and protector of Terra, marshals the defences.

Fell times have come to the galaxy. Cadia has fallen, destroyed by the onslaught of Chaos. A Great Rift in the warp has opened, and from its depths spew daemons and the horrors of Old Night. But all hope is not lost… A hero, long absent, has returned, and with him comes the wrath of the Ultramarines reborn. Roboute Guilliman has arisen to lead the Imperium out of darkness on a crusade the likes of which has not been seen since the fabled days of the Emperor. But never before have the forces of Ruin amassed in such numbers, and nowhere is safe from despoliation.

When his body is hideously damaged in an enemy attack, it looks as though Inquisitor Gideon Ravenor's promising career would be abruptly brought short. Now, encased in a life support sytem that keeps him alive but forever cuts him off from the physical world, Ravenor utilises his formidable mental powers to continue his investigations. Along with his retinue of warriors and assassins, Gideon Ravenor fights to protect an Imperium he can no longer see, hear or feel.

The shrine world of Divinatus Prime has become lost to the light of the Astronomican, and no ship can piece its veil. Only the Lord of Death himself, Blood Angels Chief Librarian Mephiston, has any hope of discerning the fate of this once pious world. After enacting a powerful blood ritual, Mephiston and an honour guard of his fellow Blood Angels reach the stricken shrine world to find it seized by religious civil war. Each faction fights for dominance of a potent artefact, the Blade Petrific, said to be wrought by the Emperor Himself.

After fleeing the authorities in the Imperial city of Altdorf, Felix Jaeger swears a drunken oath to dour dwarf Gotrek Gurnisson to record his death saga. In the cold light of day, Felix's worst fears are confirmed as he learns that Gotrek is a Trollslayer - a dwarf doomed to seek out a heroic death in battle to atone for an unknown personal disgrace. Their travels throw them into a string of extraordinary adventures as Felix tries to survive his companion's destiny.

Legend tells of a foolhardy expedition, led by the radical Magos Telok, that ventured out into the unknown space beyond the Halo Worlds in search of the 'Breath of the Gods' - an arcane device with the power to unmake and reshape the very stars themselves. Thousands of years later, the ambitious Lexell Kotov musters his Adeptus Mechanicus Explorator fleet and sets out to follow in mad old Telok's footsteps.