When Russ loses his third girlfriend in a row to his overly voracious need for getting down and dirty, he complains to his friends that a girl wouldn’t ever have this problem. Case in point: His friend Krystal, a lesbian who sleeps with dozens and dozens of hot dates. But since he’s not a girl, Krystal proposes an alternate solution: Why not go see a fortune teller and see if a little hypnosis can cure him of his appetites?

Drew Crossfield is a fashion designer with a secret desire that he's never dared to explore, no matter how badly he might want to. When famous style icon naTasha notices him, there's no turning back. She knows a closeted sissy when she sees one, and she’s determined, from the start, to change this drab dresser into the feminized glam girl of his dreams.

Sam was just another lazy kid - no direction in life, hanging out at his parents’ house, no girlfriend, listless. His parents gave him choices: move out and work the only kind of job he was ready for, a minimum-wage job, or join the service, or go to a girls’ finishing school. Sam becomes Samantha and goes off to school - a school where the girls are taught how to take care of a man and be the ideal wife.

When Charlie’s friend Vanessa crashes his gaming party and whines about the boys never wanting to have a night on the town, Charlie shoots back that he’d love to go out if he could get the kind of romantic attention she does for just one night. Without missing a beat, Vanessa offers to give him just that chance and see just what it’s like to be a gorgeous girl on the town. With his soft looks and slender body, she thinks she could make him into a rather pretty girl.... Why not, Charlie wonders? It might be fun.

When Rick, a high-powered, rich financier, unexpectedly arrives at the gates of heaven and is denied entry because of the self-centered way he lived his life, all he wants is a second chance to make up for past mistakes. He’d always intended to be more generous and kinder to people - he was just planning to do it in his golden years. When the angels give him the chance to go back to Earth in a young, fit body and prove the truth of his intentions, Rick eagerly accepts. Getting to be young all over again while keeping all of his accumulated wisdom sounds like a great deal.