Everyone thinks Emmy Dockery is crazy. Obsessed with finding the link between hundreds of unsolved cases, Emmy has taken leave from her job as an FBI researcher. Now all she has are the newspaper clippings that wallpaper her bedroom, and her recurring nightmares of an all-consuming fire. Not even Emmy's ex-boyfriend, field agent Harrison "Books" Bookman, will believe her that hundreds of kidnappings, rapes, and murders are all connected.

In Los Angeles, Detective Garrett Dobbs and FBI Agent Jessica Gimble have joined forces to work a murder that seems like a dead cinch. Their chief suspect is quickly identified and apprehended - but then there's another killing just like the one they've been investigating. And another. And not just in Los Angeles - the spree spreads across the country. The Fitzgerald family comes to the investigators' attention, but Dobbs and Gimble are at a loss - if one of the four is involved, which Fitzgerald might it be?

The murder of an Ivy League professor pulls Dr. Dylan Reinhart out of his ivory tower and onto the streets of New York, where he reunites with his old partner, Detective Elizabeth Needham. As the worst act of terror since 9/11 strikes the city, a name on the casualty list rocks Dylan's world. Is his secret past about to be brought to light? As the terrorist attack unfolds, Elizabeth Needham does something courageous that thrusts her into the media spotlight. She's a reluctant hero. And thanks to the attention, she also becomes a prime target for the ruthless murderer behind the attack.

The city of Miami is Detective Tom Moon's backyard. He's always kept it local, attending University of Miami on a football scholarship, and, as a Miami PD officer, protecting the city's most vulnerable. Now, as the new leader of an FBI task force called "Operation Guardian", it's his mission to combat international crime. Moon's investigative team discovers that the opportunistic "Blood Brothers" - Russian nationals Roman and Emile Rostoff - have evaded authorities while building a vast, powerful, and deadly crime syndicate throughout Europe and metropolitan Miami.

Prison is a dangerous place for a former cop - as Harriet Blue is learning on a daily basis. So, following a fight for her life and a prison-wide lockdown, the last person she wants to see is Deputy Police Commissioner Joe Woods. The man who put her inside. But Woods is not there to gloat. His daughter Tonya and her two-year-old child have gone missing. He's ready to offer Harriet a deal: find his family to buy her freedom....

The Inn at Gloucester stands alone on the rocky shoreline. Its seclusion suits former Boston police detective Bill Robinson, novice owner and innkeeper. As long as the dozen residents pay their rent, Robinson doesn't ask any questions. Neither does Sheriff Clayton Spears, who lives on the second floor. Then Mitchell Cline arrives, with a deadly new way of doing business. His crew of local killers break laws, deal drugs, and bring violence to the doors of the Inn. 

Angela's graduate school days at MIT come to an abrupt end when she uses her hacking skills on another student's computer. Yet her mentor, Eve Abajian, arranges a new beginning for her - as an intern in FBI's Boston field office. Her new supervisor, Assistant Special Agent in Charge William Keats, one of only two agents in the Northeast to make his rank before the age of 30, sees in Angela a fellow prodigy. But Angela's skills come with a natural curiosity, which is also a dangerous liability. 

When New York City's Mayor is desperate to find his missing daughter, Detective Michael Bennett steps in to help the Mayor and strike a deal to save his son in prison. Bennett and the mayor have always had a tense relationship, but now the mayor sees in Bennett a discreet investigator with family worries of his own. Just one father helping another. The detective leaps into the case and sources lead him to a homicide in the Bronx. The victim has ties to a sophisticated hacking operation - and also to the mayor's missing daughter, Natalie, a 21-year-old computer prodigy.  

Reality star Erin Easton's "Wedding of the Century" may have a cable crew documenting every extravagant bridal detail, but when "Airhead Easton" disappears from the reception, it's no diva turn. Her dressing room is empty but for a blood-spattered wedding gown and signs of a struggle. Detective Kylie MacDonald of NYPD Red, already on-scene as a plus-one, loops in her partner to activate level one mobilization for this PR nightmare. But when Erin's "proof of life" video makes it to air, every A-lister on the guest list becomes a target of suspicion, or just a target.

FBI Agent Atlee Pine's search for her sister Mercy clashes with military investigator John Puller's high-stakes case, leading them both deep into a global conspiracy - from which neither of them will escape unscathed.

A serial killer is loose on the streets of Manhattan. His victims appear to be total strangers. The only clue that unites the crimes is the playing card left behind at each scene that hints at the next target. The killer, known in the tabloids as The Dealer, is baiting cops into a deadly and scandalous guessing game that has the city increasingly on edge.

As the holidays approach, Detective Lindsay Boxer and her friends in the Women's Murder Club have much to celebrate. Crime is down. The medical examiner's office is quiet. Even the courts are showing some Christmas spirit. And the news cycle is so slow that journalist Cindy Thomas is on assignment to tell a story about the true meaning of the season for San Francisco. Then, a fearsome criminal known only as "Loman" seizes control of the headlines. He is planning a deadly surprise for Christmas morning.

Sally Grissom is a top secret service agent in charge of the Presidential Protection team. She knows that something is amiss when she is summoned to a private meeting with the president and his chief of staff without any witnesses. But she couldn't have predicted that she'd be forced to take on an investigation surrounding the mysterious disappearance of the first lady - with strict orders to keep it a secret. 

For a trio of colleagues, an innocent night out after class ends in a deadly torture session. They vanish without a clue - until a body turns up. With the safety of San Francisco's entire school system at stake, Lindsay has never been under more pressure. As the chief of police and the press clamor for an arrest in the "school night" case, Lindsay turns to her best friend, investigative journalist Cindy Thomas. Together, Lindsay and Cindy take a new approach to the case, and unexpected facts about the victims leave them stunned.  

Kay Willingham led a life as glamorous as it was public - she was a gorgeous Georgetown socialite, philanthropist, and the ex-wife of the vice president. So why was she parked in a Bentley convertible idling behind a DC private school, in the middle of the night, with the man who was the head of that school? Who shot them both, point blank, and why? The shocking double homicide is blazed across the internet, TV, newspapers - and across Alex Cross's mind. Kay had been his patient once. And maybe more.