Showing results by author "Dorothy H. Crawford" in All Categories

Viruses are big news. From pandemics such as HIV, swine flu, and SARS, we are constantly being bombarded with information about new lethal infections. In this Very Short Introduction, Dorothy Crawford demonstrates how clever these entities really are. From their discovery and the unravelling of their intricate structures, Crawford demonstrates how these tiny parasites are by far the most abundant life forms on the planet.

Ever since we started huddling together in communities, the story of human history has been inextricably entwined with the story of microbes. They have evolved and spread amongst us, shaping our culture through infection, disease, and pandemic. At the same time, our changing human culture has itself influenced the evolutionary path of microbes. Dorothy H. Crawford here shows that one cannot be truly understood without the other. Beginning with a dramatic account of the SARS pandemic at the start of the 21st century, she takes us back in time to follow the interlinked history of microbes and man....

The Epstein-Barr virus (EBV) was discovered in 1964. At the time, the very idea of a virus underlying a cancer was revolutionary. Cancer is, after all, not catching. Even now, the idea of a virus causing cancer surprises many people. But Epstein-Barr, named after its discoverers, Sir Anthony Epstein and Dr Yvonne Barr, is fascinating for other reasons, too. Almost everyone carries it, yet it is only under certain circumstances that it produces disease.

The hunt for the origin of the AIDS virus began over 20 years ago. It was a journey that went around the world and involved painstaking research to unravel how, when, and where the virus first infected humans. Dorothy H. Crawford traces the story back to the remote rain forests of Africa - home to the primates that carry the ancestral virus - and reveals how HIV-1 first jumped from chimpanzees to humans in rural southeast Cameroon. Examining how this happened, and how it then travelled back to Colonial west central Africa where it eventually exploded as a pandemic, she asks why and how it was able to spread so widely.