Deep in the heart of Appalachia stands a crooked farmhouse miles from any road. The Morrows keep to themselves, and it's served them well so far. When girls go missing off the side of the highway, the cops don't knock on their door. Which is a good thing, seeing what's buried in the Morrows' backyard. But 19-year-old Michael Morrow isn't like the rest of his family. He doesn't take pleasure in the screams that echo through the trees.

A group of close friends gathers at a secluded cabin in the wintry mountains of Colorado for a final holiday hurrah. Instead, it may be their last stand. First a massive blizzard leaves them marooned. Then the more chilling realization: Something is lurking in the woods, watching them, waiting.... Now a weekend of family, friends, and fun has turned into a test of love and loyalty in the face of inhuman horrors. The only hope for those huddled inside is to fight - tooth and nail, bullet and blade - for their lives. Otherwise, they’ll end up like the monsters’ other victims: bright pools of blood on glittering snow, screams lost in the vast mountains.

Mary is a quiet middle-aged woman doing her best to blend into the background. Unremarkable. Invisible. Unknown even to herself. But lately, things have been changing inside Mary. Along with the hot flashes and body aches, she can’t look in a mirror without passing out, and the voices in her head have been urging her to do unspeakable things. Fired from her job in New York, she moves back to her hometown hoping to reconnect with her past and inner self. What she finds instead are visions of terrifying mutilated specters that come with increasing regularity.

Once every year, Scoutmaster Tim Riggs leads a troop of boys into the Canadian wilderness for a weekend camping trip - a tradition as comforting and reliable as a good ghost story around a roaring bonfre. The boys are a tight-knit crew. There’s Kent, one of the most popular kids in school; Ephraim and Max, also well-liked and easygoing; then there’s Newt the nerd and Shelley the odd duck. For the most part, they all get along and are happy to be there - which makes Scoutmaster Tim’s job a little easier.

July 1995. April and Eddie have taken a wrong turn. They’re looking for the small resort town where they plan to spend their honeymoon. When they spot what appears to a lone hitchhiker along the deserted road, they stop to help. But not long after the hitchhiker gets into their car, they see the blood seeping from her jacket and a truck barreling down Atticus Line after them.