Agenda 2021 presents actions that America must take in 2021 to save America and save planet Earth. Issues, reference books, and necessary actions are specified in policy areas including: Allies, Environment, Pandemic, Defending Democracy, Racial Equality, Economic Reconstruction, Citizens United, Presidential Powers, US Senate, Truth, Sexism, Safety, Education, and Free Press.

Author Stacy Holmes warns that failure to take revolutionary action in all of these areas imperils America's future as a representative democracy and imperils the future habitability of planet Earth. Stacy Holmes is a retired public school teacher, principal, and superintendent who has researched and written Agenda 2021 out of his concern for his grandchildren and all the members of the coming generations. He sees America in 2021 at an existential crisis point with each of the policy areas he discusses at the brink of irretrievable losses.

Holmes concludes, "Either we heal the suffering, bring traitors to justice, save the unemployed from economic ruin, preserve our precious planet, make America safe for all and forge strong new bonds with our allies or 2021 is not the turning point it must be. As difficult as this work is in 2021, it will be much more difficult if not impossible in 2022. The environment, public health, the economy, national security and domestic peace - one or all - will deteriorate beyond recovery without revolutionary change in the months ahead."