It is 1995, and Anvar Faris is a restless, rebellious, and sharp-tongued boy doing his best to grow up in Karachi, Pakistan. As fundamentalism takes root within the social order and the zealots next door attempt to make Islam great again, his family decides, not quite unanimously, to start life over in California. Ironically, Anvar's deeply devout mother and his model-Muslim brother adjust easily to life in America, while his fun-loving father can't find anyone he relates to. For his part, Anvar fully commits to being a bad Muslim.

Twelve-year-old Bird Gardner lives a quiet existence with his loving father, a former linguist who now shelves books in a university library. His mother, Margaret, a Chinese American poet, left without a trace when he was nine years old. He doesn’t know what happened to her—only that her books have been banned—and he resents that she cared more about her work than about him.

When Springville residents—at least the ones still alive—are questioned about what happened on prom night, they all have the same explanation . . . Maddy did it. An outcast at her small-town Georgia high school, Madison Washington has always been a teasing target for bullies. And she's dealt with it because she has more pressing problems to manage. Until the morning a surprise rainstorm reveals her most closely kept secret: Maddy is biracial. She has been passing for white her entire life at the behest of her fanatical white father, Thomas Washington.

Olivia McAfee knows what it feels like to start over. Her picture-perfect life—living in Boston, married to a brilliant cardiothoracic surgeon, raising their beautiful son, Asher—was upended when her husband revealed a darker side. She never imagined that she would end up back in her sleepy New Hampshire hometown, living in the house she grew up in and taking over her father’s beekeeping business. Lily Campanello is familiar with do-overs, too. When she and her mom relocate to Adams, New Hampshire, for her final year of high school, they both hope it will be a fresh start.

Chemist Elizabeth Zott is not your average woman. In fact, Elizabeth Zott would be the first to point out that there is no such thing as an average woman. But it’s the early 1960s and her all-male team at Hastings Research Institute takes a very unscientific view of equality. Except for one: Calvin Evans; the lonely, brilliant, Nobel–prize nominated grudge-holder who falls in love with—of all things—her mind. True chemistry results.

Kiara and her brother, Marcus, are barely scraping by in a squalid East Oakland apartment complex optimistically called the Regal-Hi. Both have dropped out of high school, their family fractured by death and prison. But while Marcus clings to his dream of rap stardom, Kiara hunts for work to pay their rent—which has more than doubled—and to keep the nine-year-old boy next door, abandoned by his mother, safe and fed.

On a bitter-cold day, in the December of his junior year at Harvard, Sam Masur exits a subway car and sees, amid the hordes of people waiting on the platform, Sadie Green. He calls her name. For a moment, she pretends she hasn’t heard him, but then, she turns, and a game begins: a legendary collaboration that will launch them to stardom.

Laia is a Scholar living under the iron-fisted rule of the Martial Empire. When her brother is arrested for treason, Laia goes undercover as a slave at the empire's greatest military academy in exchange for assistance from rebel Scholars who claim that they will help to save her brother from execution.

Their love was supposed to last forever. But when life delivered blow after devastating blow, Yasmen and Josiah Wade found that love alone couldn’t solve or save everything. It couldn’t save their marriage. Yasmen wasn’t prepared for how her life fell apart, but she’s finally starting to find joy again. She and Josiah have found a new rhythm, co-parenting their two kids and running a thriving business together. Yet like magnets, they’re always drawn back to each other, and now they’re beginning to wonder if they’re truly ready to let go of everything they once had.

Ansel Packer is scheduled to die in twelve hours. He knows what he’s done, and now awaits execution, the same chilling fate he forced on those girls, years ago. But Ansel doesn’t want to die; he wants to be celebrated, understood. Through a kaleidoscope of women—a mother, a sister, a homicide detective—we learn the story of Ansel’s life.