Adelaide Henry carries an enormous steamer trunk with her wherever she goes. It’s locked at all times. Because when the trunk opens, people around Adelaide start to disappear. The year is 1915, and Adelaide is in trouble. Her secret sin killed her parents, forcing her to flee California in a hellfire rush and make her way to Montana as a homesteader. Dragging the trunk with her at every stop, she will become one of the “lone women” taking advantage of the government’s offer of free land for those who can tame it—except that Adelaide isn’t alone.

Gracetown, Florida. June 1950. Twelve-year-old Robbie Stephens, Jr., is sentenced to six months at the Gracetown School for Boys, a reformatory, for kicking the son of the largest landowner in town in defense of his older sister, Gloria. So begins Robbie’s journey further into the terrors of the Jim Crow South and the very real horror of the school they call The Reformatory.

Founded by the mysterious genius known as the Designer, the archipelago of Prospera lies hidden from the horrors of a deteriorating outside world. In this island paradise, Prospera’s lucky citizens enjoy long, fulfilling lives until the monitors embedded in their forearms, meant to measure their physical health and psychological well-being, fall below 10 percent. Then they retire themselves, embarking on a ferry ride to the island known as the Nursery, where their failing bodies are renewed, their memories are wiped clean, and they are readied to restart life afresh.

In the Nigerian city of Enugu, young Nwabulu, a housemaid since the age of ten, dreams of becoming a typist as she endures her employers' endless chores. She is tall and beautiful and in love with a rich man's son. Educated and privileged, Julie is a modern woman. Living on her own, she is happy to collect the gold jewelry lovestruck Eugene brings her, but has no intention of becoming his second wife. When a kidnapping forces Nwabulu and Julie into a dank room years later, the two women relate the stories of their lives as they await their fate.

From the day she watched her kindergarten teacher drop dead during a dramatic telling of Peter Rabbit, Clover Brooks has felt a stronger connection with the dying than she has with the living. After the beloved grandfather who raised her dies alone while she is traveling, Clover becomes a death doula in New York City, dedicating her life to ushering people peacefully through their end-of-life process. Clover spends so much time with the dying that she has no life of her own, until the final wishes of a feisty old woman send Clover on a trip across the country to uncover a forgotten love story.