Alex Cross is a homicide detective with a PhD in psychology. He works and lives in the ghettos of D. C. and looks like Muhammad Ali in his prime. He's a tough guy from a tough part of town who wears Harris Tweed jackets and likes to relax by banging out Gershwin tunes on his baby grand piano. But he also has two adorable kids of his own, and they are his own special vulnerabilities. Jezzie Flanagan is the first woman ever to hold the highly sensitive job as supervisor of the Secret Service in Washington.

NYPD Detective Michael Bennett is about to take on the most sinister challenge of his career. The nation has fallen into mourning after the unexpected death of a beloved former first lady, and the most powerful people in the world gather in New York for her funeral. Then the inconceivable occurs. Billionaires, politicians, and superstars of every kind are suddenly trapped within one man's brilliant and cold-blooded scenario. Bennett, father of 10, is pulled into the fray.

The "maddog" murderer who is terrorizing the Twin Cities is two things: insane and extremely intelligent. He kills for the pleasure of it and thoroughly enjoys placing elaborate obstacles to keep police befuddled. Each clever move he makes is another point of pride. But when the brilliant Lieutenant Lucas Davenport, a dedicated cop and a serial killer's worst nightmare, is brought in to take up the investigation, the maddog suddenly has an adversary worthy of his genius.

Along Came a Spider first introduced Alex Cross, the brilliant homicide detective. When the daughter of a Hollywood actress and the son of the Secretary of the Treasury are kidnapped, Cross and the Secret Service are pitted against Gary Soneji, a murderous serial kidnapper who wants to commit the crime of the century.

Attorney Rhonda Bird returns home after a long estrangement when she learns her father has died. There she makes two important discoveries: Her father stopped being an accountant and had opened up a private detective agency, and she has a teenage half sister named Baby. Baby brings in a client to the detective agency, a young man who claims he was abducted.