Bartholomew Lampion is born on a day of tragedy and terror that will mark his family forever. All agree that his unusual eyes are the most beautiful they have ever seen. On this same day, a thousand miles away, a ruthless man learns that he has a mortal enemy named Bartholomew. He embarks on a relentless search to find this enemy, a search that will consume his life. And a girl is born from a brutal rape, her destiny mysteriously linked to Barty and the man who stalks him.

A writer in California. A doctor in Boston. A motel owner and his employee in Nevada. A priest in Chicago. A robber in New York. A little girl in Las Vegas. They’re a handful of people from across the country, living through eerie variations of the same nightmare.

Quinn Quicksilver was born a mystery—abandoned at three days old on a desert highway in Arizona. Raised in an orphanage, never knowing his parents, Quinn had a happy if unexceptional life. Until the day of “strange magnetism.” It compelled him to drive out to the middle of nowhere. It helped him find a coin worth a lot of money. And it practically saved his life when two government agents showed up in the diner in pursuit of him. Now Quinn is on the run from those agents and who knows what else, fleeing for his life.

In retreat from a devastating loss and crushing injustice, Katie lives alone in a fortresslike stone house on Jacob’s Ladder island. Once a rising star in the art world, she finds refuge in her painting. The neighboring island of Ringrock houses a secret: a government research facility. And now two agents have arrived on Jacob’s Ladder in search of someone—or something—they refuse to identify. Although an air of menace hangs over these men, an infinitely greater threat has arrived, one so strange even the island animals are in a state of high alarm.

A decade ago, Emily Carlino vanished after her car broke down on a California highway. She was presumed to be one of serial killer Ronny Lee Jessup’s victims whose remains were never found. Writer David Thorne still hasn’t recovered from losing the love of his life, or from the guilt of not being there to save her. Then David meets Maddison Sutton, beguiling, playful, and keenly aware of all David has lost. But what really takes his breath away is that everything about Maddison, down to her kisses, is just like Emily.