Addie Downs and Valerie Adler will be best friends forever. That’s what Addie believes after Valerie moves across the street when they’re both nine years old. But in their teenage years, Val is swept into the popular crowd. Flash-forward 15 years. Addie Downs lives alone in her parents’ house, caring for a troubled brother and trying to meet Prince Charming on the Internet. she opens her door to find her long-gone best friend standing there, a terrified look on her face and blood on the sleeve of her coat.

When her twenty-two-year-old stepdaughter announces her engagement to her pandemic boyfriend, Sarah Danhauser is shocked. But the wheels are in motion. Headstrong Ruby has already set a date (just three months away!) and spoken to her beloved safta, Sarah’s mother Veronica, about having the wedding at the family’s beach house in Cape Cod. Sarah might be worried, but Veronica is thrilled to be bringing the family together one last time before putting the big house on the market.

Jules Strauss is a Princeton senior with a full scholarship, acquaintances instead of friends, and a family she's ashamed to invite to Parents' Weekend. With the income she'll receive from donating her "pedigree" eggs, she believes she can save her father from addiction.

Meet Rose Feller. She's 30 years old and a high-powered attorney with a secret passion for romance novels. She dreams of a man who will slide off her glasses, gaze into her eyes, and tell her that she's beautiful. She also dreams of getting her fantastically screwed-up little sister to get her life. together. Meet Rose's sister, Maggie. Twenty-eight years old, drop-dead gorgeous and only occasionally employed. Although her dreams of big-screen stardom haven't progressed, Maggie dreams of fame and fortune - and of getting her dowdy big sister to stick to a skin-care regime.

Cannie Shapiro never wanted to be famous. The smart, sharp, plus-sized pop culture reporter was perfectly content writitng about other people's lives in the pages of the Philadlphia Examiner. But the day she opened up a national women's magazine to find out that her ex-boyfriend has been chronicling their ex-sex life is the day her life changes forever.