Forty-eight hours after leaving her husband's body at the base of the stairs, Tanya Dubois cashes in her credit cards, dyes her hair brown, demands a new name from a shadowy voice over the phone, and flees town. It's not the first time. She meets Blue, a female bartender who recognizes the hunted look in a fugitive's eyes and offers her a place to stay. With dwindling choices, Tanya-now-Amelia accepts. An uneasy - and dangerous - alliance is born.

Felix Castor is a freelance exorcist, and London is his stomping ground. It may seem like a good ghostbuster can charge what he likes and enjoy a hell of a lifestyle, but there's a risk: sooner or later he's going to take on a spirit that's too strong for him. When Castor accepts a seemingly simple ghost-hunting case at a museum in the shadowy heart of London, what should have been a perfectly straightforward exorcism is rapidly turning into the Who Can Kill Castor First Show, with demons and ghosts all keen to claim the big prize.

Curiosities opens with a present-day amateur historian, Anne, who describes her unexpected discovery of five seventeenth-century manuscripts that, astonishingly, tell the same strange story from vastly different points of view. The five manuscripts spin this tale: after the Plague descends upon a village in England, two small children, Joan and Thomasina, are the only survivors.

When Ralph and Abby Lamb move in with Ralph’s mother, Laura, Abby hopes it’s just what she and her mother-in-law need to finally connect. After a traumatic childhood, Abby is desperate for a mother figure, especially now that she and Ralph are trying to become parents themselves. Abby just has so much love to give—to Ralph, to Laura, and to Mrs. Bondy, her favorite resident at the long-term care home where she works. But Laura isn’t interested in bonding with her daughter-in-law. She’s venomous and cruel, especially to Abby, and life with her is hellish.

Curator of paleontology Dr. Simon Nealy never expected to return to his Pennsylvania hometown, let alone the Hawthorne Museum of Natural History. He was just a boy when his six-year-old sister, Morgan, was abducted from the museum under his watch, and the guilt has haunted Simon ever since. After a recent breakup and the death of the aunt who raised him, Simon feels drawn back to the place where Morgan vanished, in search of the bones they never found.