Franny Stone has always been the kind of woman who is able to love but unable to stay. Leaving behind everything but her research gear, she arrives in Greenland with a singular purpose: to follow the last Arctic terns in the world on what might be their final migration to Antarctica. Franny talks her way onto a fishing boat, and she and the crew set sail, traveling ever further from shore and safety. But as Franny’s history begins to unspool - a passionate love affair, an absent family, a devastating crime - it becomes clear that she is chasing more than just the birds.

After Tova Sullivan’s husband died, she began working the night shift at the Sowell Bay Aquarium, mopping floors and tidying up. Keeping busy has always helped her cope, which she’s been doing since her eighteen-year-old son, Erik, mysteriously vanished on a boat in Puget Sound over thirty years ago. Tova becomes acquainted with curmudgeonly Marcellus, a giant Pacific octopus living at the aquarium. Marcellus knows more than anyone can imagine but wouldn’t dream of lifting one of his eight arms for his human captors—until he forms a remarkable friendship with Tova.

After the untimely deaths of her aunt and mother, young Riley Mays moved from Chicago to her cousins’ Wisconsin farm. Here she found solace in caring for her extraordinary adoptive brother, exploring the surrounding wild nature, and gazing at the mystical moon - a private refuge in which she hides from her most painful memories. But ten years later, now twenty-one, Riley feels too confined by the protective walls she’s erected around herself. When a stranger enters her family’s remote world, Riley senses something he’s hiding, a desire to escape that she understands well.

Moments after Lisbeth is born, she’s taken from her mother and handed over to an enslaved wet nurse, Mattie, a young mother separated from her own infant son in order to care for her tiny charge. Thus begins an intense relationship that will shape both of their lives for decades to come. Though Lisbeth leads a life of privilege, she finds nothing but loneliness in the company of her overwhelmed mother and her distant, slave-owning father.

Rosalind Franklin has always been an outsider - brilliant, but different. Whether working at the laboratory she adored in Paris or toiling at a university in London, she feels closest to the science, those unchanging laws of physics and chemistry that guide her experiments. When she is assigned to work on DNA, she believes she can unearth its secrets. Rosalind knows if she just takes one more X-ray picture - one more after thousands - she can unlock the building blocks of life.