Lincoln Rhyme was once a brilliant criminologist, a genius in the field of forensics - until an accident left him physically and emotionally shattered. But now a diabolical killer is challenging Rhyme to a terrifying and ingenious duel of wits. With police detective Amelia Sachs by his side, Rhyme must follow a labyrinth of clues that reaches back to a dark chapter in New York City’s past - and reach further into the darkness of the mind of a madman who won’t stop until he has stripped life down to the bone.

Ten years ago in California, Daniel Pell, a self-styled Charles Manson, was sentenced to life in prison for murdering an entire family: husband, wife, and two children, plus one of his young male followers. He is brought to Salinas, California, to interview with Kathryn Dance after he is implicated in yet another killing. Things go terribly wrong during an interview break, and Pell escapes, intent on killing again.

In a secluded farm house in the Pacific Northwest, a family has been slaughtered - and a teenage son has disappeared. Single mother and cop Emily Kenyon spearheads a dark hunt for a killer. But Emily's teenage daughter, Jenna, is one step ahead of her. Then another family is butchered, and another. As Emily fits the puzzle pieces together, she makes a chilling discovery: The killer is coming after her and her daughter....

On the night he celebrates a big win, defense attorney Mickey Haller is pulled over by police, who find the body of a former client in the trunk of his Lincoln. Haller is immediately charged with murder but can’t post the exorbitant $5 million bail. Mickey elects to represent himself and is forced to mount his defense from his jail cell in downtown Los Angeles. Even if he can obtain a not-guilty verdict, Mickey understands that it won’t be enough. In order to be truly exonerated, he must find out who really committed the murder and why. That is the law of innocence.

Twenty years ago in the dead of night, four seemingly random individuals pulled the ultimate heist and almost walked away with half a million dollars. But by daybreak, their plan had been shot to hell. One of them was in the hospital. One was in jail. One was dead. And one got away with it. Arden Maxwell, the daughter of the man who disappeared all those years ago - presumably with the money, after murdering his accomplice - has never reconciled with her father's abandonment of her and her sister.