Single mom Jess Davis is a data and statistics wizard, but no amount of number crunching can convince her to step back into the dating world. After all, her father was never around, her hard-partying mother disappeared when she was six, and her ex decided he wasn’t “father material” before her daughter was even born. Jess holds her loved ones close but working constantly to stay afloat is hard...and lonely. But then Jess hears about GeneticAlly, a buzzy new DNA-based matchmaking company that’s predicted to change dating forever.

The many lives of theoretical physicist Elsie Hannaway have finally caught up with her. By day, she’s an adjunct professor, toiling away at grading labs and teaching thermodynamics in the hopes of landing tenure. By other day, Elsie makes up for her non-existent paycheck by offering her services as a fake girlfriend, tapping into her expertly honed people-pleasing skills to embody whichever version of herself the client needs. Honestly, it’s a pretty sweet gig—until her carefully constructed Elsie-verse comes crashing down.

Harriet and Wyn have been the perfect couple since they met in college—they go together like salt and pepper, honey and tea, lobster and rolls. Except, now—for reasons they’re still not discussing—they don’t. They broke up five months ago. And still haven’t told their best friends. Which is how they find themselves sharing a bedroom at the Maine cottage that has been their friend group’s yearly getaway for the last decade.

After a wild bet, gourmet grilled-cheese sandwich, and cuddle with a baby goat, Alexis Montgomery has had her world turned upside down. The cause: Daniel Grant, a ridiculously hot carpenter who’s ten years younger than her and as casual as they come—the complete opposite of sophisticated city-girl Alexis. And yet their chemistry is undeniable.

Prepared for a good time, Tessa is thrilled to spend the weeks before her sister’s wedding at their family’s favorite vacation spot: Santorini. Sandy beaches, stonewashed houses, attractive men—it’s heaven. But Tessa’s idea of a girls’ trip comes to a screaming halt when her sister thinks it’s high time Tessa finds some love herself. Unfortunately, Tessa forgot about the deal she made back in high school: she has to find her soulmate before her sister’s wedding. Or else.

Hallie Piper is turning over a new leaf. After belly-crawling out of a hotel room (hello, rock bottom), she decides it’s time to become a full-on adult. She gets a new apartment, a new haircut, and a new wardrobe, but when she logs onto the dating app that she has determined will find her new love, she sees none other than Jack, the guy whose room she snuck out of.

Sally Milz is a sketch writer for The Night Owls, a late-night live comedy show that airs every Saturday. With a couple of heartbreaks under her belt, she’s long abandoned the search for love, settling instead for the occasional hook-up, career success, and a close relationship with her stepfather to round out a satisfying life. But when Sally’s friend and fellow writer Danny Horst begins dating Annabel, a glamorous actress who guest-hosted the show, he joins the not-so-exclusive group of talented but average-looking and even dorky men at the show.

Growing up the daughter of notorious treasure hunter and absentee father Duke Wilder left Lily without much patience for the profession…or much money in the bank. But Lily is resourceful, and now uses Duke’s coveted hand-drawn maps to guide tourists on fake treasure hunts through the red rock canyons of Utah. It pays the bills but doesn’t leave enough to fulfill her dream of buying back the beloved ranch her father sold years ago, and definitely not enough to deal with the sight of the man she once loved walking back into her life with a motley crew of friends ready to hit the trails.

Now. Kathleen Rosenberg is okay with her ordinary existence, and leaving her pop star image in the past. That is, until Cal Kirby shows up with the opportunity of her dreams—a starring role in the Broadway show he’s directing and a chance to perform the way she’s always wanted. The two haven’t spoken since the joint destruction of their careers, and each of them blames the other, making their reunion a tense battle of wits and egos.

Olive Torres is used to being the unlucky twin: from inexplicable mishaps to a recent layoff, her life seems to be almost comically jinxed. By contrast, her sister Ami is an eternal champion...she even managed to finance her entire wedding by winning a slew of contests. Unfortunately for Olive, the only thing worse than constant bad luck is having to spend the wedding day with the best man (and her nemesis), Ethan Thomas.

Nora Mackenzie’s entire career lies in the hands of famous NFL tight end Derek Pender, who also happens to be her extremely hot college ex-boyfriend. Nora didn’t end things as gracefully as she could have back then, and now it has come back to haunt her. Derek is her first client as an official full-time sports agent and he’s holding a grudge.

Carey Duncan has worked for home remodeling and design gurus Melissa and Rusty Tripp for nearly a decade. A country girl at heart, Carey started in their first store at 16, and - more than anyone would suspect - has helped them build an empire. With a new show and a book about to launch, the Tripps are on the verge of superstardom. There’s only one problem: America’s favorite couple can’t stand each other.

With a world-famous speaker at their university, Millie Morris and her four woefully single male colleagues make a pact that they’ll all find dates. Unfortunately, Millie has more success helping them make matches online than she does navigating the onslaught of lewd pics in her own feed. But when she creates a fictional name for a new account, Millie finds herself vying for the online attention of a man she sees every day in the flesh.

Kristen Petersen doesn't do drama, will fight to the death for her friends, and has no room in her life for guys who just don't get her. She's also keeping a big secret: facing a medically necessary procedure that will make it impossible for her to have children. Planning her best friend's wedding is bittersweet for Kristen - especially when she meets the best man, Josh Copeland. He's funny, sexy, never offended by her mile-wide streak of sarcasm, and always one chicken enchilada ahead of her hangry. Even her dog, Stuntman Mike, adores him. The only catch: Josh wants a big family.

Macy Sorensen is settling into an ambitious if emotionally tepid routine: work hard as a new pediatrics resident, plan her wedding to an older, financially secure man, keep her head down and heart tucked away. But when she runs into Elliot Petropoulos - the first and only love of her life - the careful bubble she’s constructed begins to dissolve.