Tessa Russo is the mother of two young children and the wife of a renowned pediatric surgeon. Despite her own mother's warnings, Tessa has recently given up her career to focus on her family and the pursuit of domestic happiness. From the outside, she seems destined to live a charmed life. Valerie Anderson is an attorney and single mother to six-year-old Charlie - a boy who has never known his father.

It’s 2 a.m. on a Saturday night in the spring of 2001, and 28-year-old Cecily Gardner sits alone in a dive bar in New York’s East Village, questioning her life. Feeling lonesome and homesick for the Midwest, she wonders if she’ll ever make it as a reporter in the big city - and whether she made a terrible mistake in breaking up with her longtime boyfriend, Matthew. As Cecily reaches for the phone to call him, she hears a guy on the barstool next to her say, “Don’t do it - you’ll regret it.” Something tells her to listen.

Thirty-three-year-old Shea Rigsby has spent her entire life in Walker, Texas - a small college town that lives and dies by football, a passion she unabashedly shares. Raised alongside her best friend, Lucy, the daughter of Walker’s legendary head coach, Clive Carr, Shea was too devoted to her hometown team to leave. Instead she stayed in Walker for college, even taking a job in the university athletic department after graduation, where she has remained for more than a decade.

Nina Browning is living the good life after marrying into Nashville's elite. More recently, her husband made a fortune selling his tech business, and their adored son has been accepted to Princeton. Yet sometimes the middle-class small-town girl in Nina wonders if she's strayed from the person she once was. Tom Volpe is a single dad working multiple jobs while struggling to raise his headstrong daughter, Lyla. His road has been lonely, long, and hard, but he finally starts to relax after Lyla earns a scholarship to Windsor Academy, Nashville's most prestigious private school.

Growing up, Josie and Meredith Garland shared a loving, if sometimes contentious, relationship. Josie was impulsive, spirited, and outgoing, Meredith hardworking, thoughtful, and reserved. When tragedy strikes, their delicate bond splinters. Fifteen years later, Josie and Meredith are in their late 30s, following very different paths.  

Ellen's relationship to Andy doesn't just seem perfect on the surface; it really is perfect. She loves his family, and everything about him, including that he brings out the best in her. That is, until Ellen unexpectedly runs into Leo. The one who got away. The one who brought out the worst in her. The one she can't forget.

Darcy Rhone thought she had it all figured out: the more beautiful the girl, the more charmed her life. Never mind substance. Never mind playing by the rules. Never mind karma. But Darcy's neat, perfect world turns upside down when her best friend, Rachel, the plain-Jane “good girl,” steals her fiancé, while Darcy finds herself completely alone for the first time in her life . . . with a baby on the way. Darcy tries to recover, fleeing to her childhood friend living in London and resorting to her tried-and-true methods for getting what she wants.

When it comes to relationships, 34-year-old Kate Turner is ready to say "Bah, humbug". The sleepy town of Blexford, England, isn't exactly brimming with prospects, and anyway, Kate's found fulfillment in her career as a designer and in her delicious side job baking for her old friend Matt's neighborhood café. But then her best friend signs her up for a dating agency that promises to help singles find love before the holidays. Twenty-three days until Christmas. Twelve dates with 12 different men. The odds must finally be in her favor...right?

Rachel White is the consummate good girl. A hard-working attorney at a large Manhattan law firm and a diligent maid of honor to her charmed best friend Darcy, Rachel has always played by all the rules. But that changes the night of her thirtieth birthday when Rachel finally confesses her feelings to Darcy's fiancé, and is both horrified and thrilled to discover that he feels the same way. As the wedding date draws near, events spiral out of control, and Rachel knows she must make a choice between her heart and conscience.

Bea Schumacher is a devastatingly stylish plus-size fashion blogger who has amazing friends, a devoted family, legions of Insta followers - and a massively broken heart. Like the rest of America, Bea indulges in her weekly obsession: the hit reality show Main Squeeze. The fantasy dates! The kiss-off rejections! The surprising amount of guys named Chad! But Bea is sick and tired of the lack of body diversity on the show. Since when is being a size zero a prerequisite for getting engaged on television? Just when Bea has sworn off dating altogether, she gets an intriguing call.

Trevor Benson never intended to move back to New Bern, North Carolina. But when a mortar blast outside the hospital where he worked as an orthopedic surgeon sent him home from Afghanistan with devastating injuries, the dilapidated cabin he'd inherited from his grandfather seemed as good a place to regroup as any.

Growing up in 1950s Detroit, they live in a perfect “Dick and Jane” house, where their roles in the family are clearly defined. Jo is the tomboy, the bookish rebel with a passion to make the world more fair; Bethie is the pretty, feminine good girl, a would-be star who enjoys the power her beauty confers and dreams of a traditional life. But the truth ends up looking different from what the girls imagined. Jo and Bethie survive traumas and tragedies.

Becky still adores the traditions of Christmas: Her parents host, carols play on repeat, her mother pretends she made the Christmas pudding, and the neighbors come ’round for sherry in their terrible holiday sweaters. Things are looking cheerier than ever, until Becky’s parents announce they’re moving to ultra-trendy Shoreditch - unable to resist the draw of craft beer and smashed avocados - and ask Becky if she’ll host this year. What could possibly go wrong? 

Six years after the fight that ended their friendship, Daphne Berg is shocked when Drue Cavanaugh walks back into her life, looking as lovely and successful as ever, with a massive favor to ask. Daphne hasn’t spoken one word to Drue in all this time - she doesn’t even hate-follow her ex-best friend on social media - so when Drue asks if she will be her maid-of-honor at the society wedding of the summer, Daphne is rightfully speechless.

A year ago, Irene Steele had the shock of her life: her loving husband, father to their grown sons and successful businessman, was killed in a helicopter crash. But that wasn't Irene's only shattering news: He'd also been leading a double life on the island of St. John, where another woman loved him, too. Now Irene and her sons are back on St. John, determined to learn the truth about the mysterious life - and death - of a man they thought they knew. Along the way, they're about to learn some surprising truths about their own lives, and their futures.