#1 FBS vs Human Serum in Cell culture
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#1 FBS vs Human Serum in Cell culture
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Today I want to start with one of the most common questions I hear from researchers, diagnostic developers and viral vector teams:
“Should we use FBS or Human Serum — and does it actually make a difference?”
And the short answer is:
Yes. It makes a big difference.
But not always in the way people expect.
Most labs choose serum based on tradition.
“We’ve always used FBS.”
Or: “We switched to Human Serum once and it didn’t work.”
But when you look closer, you realize something important:
The choice between FBS and Human Serum isn’t about which one is “better,” but about what you need to achieve in your specific model.
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