In this episode Dr's J and Santhosh explore the history of off label prescribing of medications. Along the way they cover literature and the rise of food safety, the importance of legal phrasing, false statements versus false advertising, sulfanilamide tragedy of 1937, the creation of prescription and over the counter medications, the thalidomide scandal and the us physician who mostly prevented it, drug repurposing and some famous examples of off label uses for medication. So sit back and relax as we read the fine print on off label medications!

Further Reading

https://pmc.ncbi.nlm.nih.gov/articles/PMC8508135/#:~:text=Off%2Dlabel%20practice%20is%20a,scope%20of%20the%20marketing%20authorization.

chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://www.fda.gov/files/about%20fda/published/The-Sulfanilamide-Disaster.pdf

https://www.pharmacytimes.com/view/pharmacys-past-the-soothing-syrup-known-for-causing-death-in-thousands-of-babies-#:~:text=Mrs.,to%20kill%20the%20average%20child.

https://www.medrxiv.org/content/10.1101/2022.09.08.22279709v1.full

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