59: Colchicine Efficacy and Safety After Myocardial Infarction
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59: Colchicine Efficacy and Safety After Myocardial Infarction
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This episode does a deep dive into a clinical trial article, "Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction." The study, known as the COLCOT trial, was a randomized, double-blind, placebo-controlled trial involving 4745 patients who had recently suffered a myocardial infarction, aiming to evaluate the effectiveness of low-dose colchicine, an anti-inflammatory medication, in preventing subsequent ischemic cardiovascular events.
Tardif JC, Kouz S, Waters DD, Bertrand OF, Diaz R, Maggioni AP, et al. Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction. N Engl J Med. 2019;381(26):2497-2505. doi:10.1056/NEJMoa1912388.
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