Welcome to the November 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the November 2025 issue of Diabetes.

6:00 In the first segment, our hosts are joined by Kaylia Reynolds, MS and Nora Franceschini, MD, MPH, FAHA, both of the Department of Epidemiology at the Gillings School of Global Public Health at the University of North Carolina. Their paper, "Diabetes Genetic Clusters and Clinical Outcomes in American Indians," is available for free at doi.org/10.2337/db25-0322.

20:40 To discuss the latest Paper of the Month, our hosts are joined by first author Stephanie K. Holm, a postdoctoral student in the Clemmensen group, and Christoffer Clemmensen, Associate Professor in the Novo Nordisk Foundation Center for Basic Metabolic Research at the University of Copenhagen. Their paper, "Sustained Weight Loss With Combined LEAP2 and Semaglutide Treatment in Mice," is available for free at doi.org/10.2337/db24-1056.

38:15 In the latest edition of "Sweet Talk," Kevin and Kirk speak with Banting Medal recipient Jens Juul Holst, MD, DMSc, of the University of Copenhagen, whose work with incretin hormones laid the foundation for therapies now used around the world. His article, "Treatment of Type 2 Diabetes and Obesity on the Basis of the Incretin System: The 2021 Banting Medal for Scientific Achievement Award Lecture," is available for free at doi.org/10.2337/dbi21-0026.

To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the October 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the October 2025 issue of Diabetes.

5:50 In the first segment, our hosts are joined by Tessa M. Cacciottolo, PhD, a Chain Florey TTI Fellow in the MRC Laboratory of Medical Sciences at Imperial College London. She is the first author of the article "Glucagon Receptor Deficiency Causes Early-Onset Hepatic Steatosis," available for free at doi.org/10.2337/db25-0209.

22:15 In honor of last month being Childhood Obesity Month, in this month's edition of "Sweet Talk", our hosts speak with Kristen Nadeau, MD, MS, a professor of pediatrics at the University of Colorado Anschutz Medical Campus, and Bethany Cartwright, MD, PhD, an Assistant Instructor in the Department of Pediatrics at UT Southwestern Medical Center. They discuss the complications children with obesity can face, as well as the stigma and weight biases that accompany these diagnoses. Cartwright's article, "Adipose Tissue as a Target for Precision Medicine Approaches in Childhood Obesity," is available for free at doi.org/10.2337/dbi24-0044.

49:10 In a special segment, Nadeau and Cartwright take questions directly from kids of various ages on the topics of diabetes and obesity.

To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the September 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the September 2025 issue of Diabetes.

5:25 In the first segment, our hosts are joined by Carmelo Quarta, PhD, a principal investigator at INSERM (National Institute of Health and Medical Research) and a group leader at the Bordeaux Neurocampus at the University of Bordeaux in France. He is the co-corresponding author of "GLP-1–Mediated Targeting of Inflammation Corrects Obesogenic Memory in Male Mice," available for free at doi.org/10.2337/db24-1071.

27:30 Next, Darleen and Kirk speak with Willa A. Hsueh, MD, Professor of Medicine in the Division of Endocrinology at the Ohio State University College of Medicine. She is a corresponding author on this month's Paper of the Month, "The GLP-1 Receptor Agonist Dulaglutide Attenuates Hepatic Steatosis in Obesity via a Weight-Independent Mechanism," available for free at doi.org/10.2337/db24-0861.

46:20 Lastly, in this month's edition of "Sweet Talk," Kevin and Darleen are joined by Alexander R. Nectow, MD, PhD. A recipient of the American Diabetes Association's Pathway to Stop Diabetes Award, Dr. Nectow lab at Columbia University studies the dorsal raphe nucleus (DRN) and its relation to metabolism. His article, "The Dorsal Raphe Nucleus and the Integrative Control of Feeding: A Report on Research Supported by Pathway to Stop Diabetes," is available for free at doi.org/10.2337/dbi24-0015.

To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!