Épisodes

  • Visual Thinking part 1: Neurobiology & Autistic's Intense Inner World
    Sep 17 2025

    Today's episode is all about visual thinking. We will explore vivid mental imagery and sensory processing. We will cover why Autistic individuals process detailed "pictures and movies" in the mind, exemplified by an anecdote of visualizing oak tree bark with tactile detail. Sensory challenges are highlighted, with a Bee Movie analogy illustrating the intense, efficient visual input. The Autistic sensory journey is described as fast but rocky, contrasting with non-autistic processing. Hyperconnectivity in visual pathways amplifies detail-oriented cognition, often leading to sensory overload.

    The episode explains how retinal ganglion cells and visual cortex hyperactivity enhance imagery in Autism. Kanner and Asperger’s observations underscore visual memory strengths and technical interests, like pattern recognition. Increased mini-column density and reduced inhibition boost local processing but risk overload. Temple Grandin’s insights show visual thinking’s strengths in tasks like designing animal pathways, though social tasks challenge due to weaker prefrontal connectivity. The Autistic brain’s wiring is framed as a unique strength, fostering intense, detailed cognition

    Temple Grandin https://www.templegrandin.com/templegrandinbooks.html

    Sensory Processing part 1 https://youtu.be/HTnFm8nY4oY?si=4Xso_tI_hMwhY_SX

    Sensory Processing part 2 https://youtu.be/n31gyLb4ddM?si=CouaBhiVm8KixtG-

    Supplementing Relationships part 1 https://youtu.be/lglEGQ7pSlc?si=ncpla784LxOyUcQc

    Supplementing Relationships part 2 https://youtu.be/W8E2B7Qu4mg?si=UJE850SwvPmtOmEk

    Daylight Computer Company

    use "autism" for $50 off at

    https://buy.daylightcomputer.com/autism

    Chroma Light Devices

    use "autism" for 10% discount at

    https://getchroma.co/?ref=autism

    00:00 Introduction to Visual Thinking

    02:00 Anecdote: Oak Tree Visualization; tree bark, tactile

    05:50 Sensory Processing Challenges; overload, information rate, avoidance

    09:40 Anecdote: Bee Movie Analogy; synchronized, intense, fast

    13:30 Autistic Sensory Rates/Speeds

    17:20 Eye Biology and Neural Relays; Retinal ganglion, SHANK3; Building Models details-to-general

    21:10 Magnocellular vs. Parvocellular Pathways; Motion, color, glutamate, GABA signaling

    25:00 Visual Cortex Hyperactivity; V1-V4, fMRI, synaptic pruning, details

    28:50 Mini-Columns and Sensory Overload; Neural units, inhibition, dense connections

    32:40 Kanner and Asperger Insights; Social isolation, technical interests, patterns

    38:39 Daylight Computer Company (and Daylight KIDS !), use "autism" for $50 discount

    40:54 Chroma Light Devices, use "autism" for 10% discount

    44:07 Reviews/Ratings & Contact Info

    X: https://x.com/rps47586

    YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA

    email: info.fromthespectrum@gmail.com

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    45 min
  • Parvalbumin Interneurons & the Autistic Phenotype
    Sep 8 2025

    Today's episode is about excitation-inhibition with specific attention with an inhibitory neuron called parvalbumin interneurons (PVINs). The discussion covers the medial prefrontal cortex, insular cortex, and salience network, linking their dysfunction to autistic traits like sensory over-responsiveness and social deficits. We cover two articles, alongside the CNTNAP2 protein’s role in neural circuit organization and its implications for Autism.

    The episode also critiques the 1985 theory of mind framework, emphasizing autistic strengths in interoception and intuition, which suggest a sensory-social trade-off that enhances learning and information processing. PVIN hypofunction is connected to social deficits and rigid thinking, supported by a 2017 post-mortem study showing a 38-70% reduction in prefrontal PVINs. The discussion integrates prior research on salience network hyper-connectivity and emotional processing deficits in autism.

    Daylight Computer Company

    use "autism" for $50 off at

    https://buy.daylightcomputer.com/autism

    Chroma Light Devices

    use "autism" for 10% discount at

    https://getchroma.co/?ref=autism

    00:00 - Parvalbumin Interneurons

    Fujima et al., social familiarity, emotion recognition, graphical abstract.

    02:03 - Neuron Interactions

    PVIN activity, social interactions, familiar/stressed peers, pyramidal neurons, excitation-inhibition balance.

    04:10 - Daylight Computer use "autism" for $50 discount

    06:38 - Chroma Light Devices use "autism" for 10% discount

    09:46 - Medial Prefrontal Cortex in Autism

    Decision-making, social cognition, self-referential thinking, anterior cingulate cortex

    12:38 - Insular Cortex and Salience Network

    Insular cortex, anterior insula, salience network, emotional states, bodily signals, social cues, autistic intuition.

    15:06 - Parvalbumin Interneurons

    PVINs, GABAergic, fast-spiking, cortex/hippocampus/basal ganglia, inhibition, neural synchronization, social/emotional processing.

    17:08 - Fujima et al. Study Methodology and Behavioral Effects

    Microendoscopic calcium imaging, chemogenetic manipulation, mice, social familiarity, emotional recognition, context-dependent behaviors, pyramidal modulation.

    21:22 - Tsang et al. Study on Infant Salience Network

    six-week-old infants, salience network, sensorimotor/prefrontal connectivity, sensory over-responsiveness, social attention, autism likelihood.

    25:22 - Salience Network and Autism Research

    Salience network hyper-connectivity, sensory processing, alexithymia, anterior insula, emotional processing deficits, autism studies (2013, 2016, 2024).

    27:44 - CNTNAP2 and PVIN Dysfunction

    Neural circuits, synaptic function, dendritic arborization, PVIN reduction, social deficits, 2017 post-mortem study.

    32:00 - Autistic Interoception and Theory of Mind

    Intuition, sensory-social trade-off, theory of mind, learning/information processing.

    34:00 - Closing

    X: https://x.com/rps47586

    YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA

    email: info.fromthespectrum@gmail.com

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    35 min
  • Tristan Scott & Daylight Computer Company’s Revolution in Human-Friendly Tech
    Sep 1 2025

    My guest today is Tristan Scott, an electrical engineer and head of operations at Daylight Computer Company. Tristan delivers a dynamic discussion on redefining technology for human health, blending personal anecdotes with technical insights. His expertise on electromagnetic fields (EMFs) and blue light’s impact drives the conversation, illuminating Daylight’s mission to create human-friendly technology.

    The episode explores the harmful effects of modern screens, particularly on children, with Tristan sharing data on developmental delays and technology’s addictive design, akin to a casino’s flashing lights. He highlights Daylight’s DC1 computer, explaining its flicker-free and blue-light-free design, which reduces eye strain and fosters a less addictive digital experience. In addition, we will discuss some issues with Autism's sensory-processing phenomena and the benefits of the DC1 computer from Daylight. The episode wraps up with an inspiring discussion on Daylight’s Kids initiative, a hopeful vision for a healthier tech future, making this episode a must-listen for anyone concerned about technology’s impact on well-being.

    Daylight Computer Company https://daylightcomputer.com

    Kids Daylight (!) https://kids.daylightcomputer.com

    Daylight Computer Company Instagram https://www.instagram.com/daylightco/?hl=en

    Daylight Kids Facebook https://www.facebook.com/groups/1300308801490853

    Daylight Computer Company X https://x.com/daylightco

    Tristan Scott Instagram https://www.instagram.com/tristan_health/?hl=en

    Tristan Scott X https://x.com/bitcoinand_beef

    Tristan's Book https://www.amazon.com/Bitcoin-Beef-Criticisms-Similarities-Decentralization/dp/B09W799F5F

    Daylight Computer Company

    use "autism" for $50 off at

    https://buy.daylightcomputer.com/autism

    Chroma Light Devices

    use "autism" for 10% discount at

    https://getchroma.co/?ref=autism

    0:00 Tristan Scott

    1:09 Tristan's path into holistic health, electrical engineering, & Daylight Computer Company; EMF Harms

    10:35 Daylight's Mission and DC1 Computer; Importance of Natural Light

    14:10 The Future of Tech (is already here with Daylight) & Children & Human Health

    16:54 Daylight's unique approach to Tech

    20:19 The Role of Tech in Modern Life; Tech Designed for Humans, not Against Humans

    23:10 Technology and Casinos (Same Trap); Dopamine Trap; Addictive and Maladaptive Behaviors

    33:25 Creating Synergy between Humans and Tech

    36:34 Understanding Sensory Processing & Autism

    42:32 Dangers of Light Flicker & The Harms for the Nervous System

    52:52 Daylight's Kids Initiative; Tech Designed for Humans & Kids

    01:02:35 Daylight's Future in Technology and Beyond

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    1 h et 15 min
  • Dr. Nirosha Murugan: Biophotons Illuminating Life with Energy & Information
    Aug 25 2025

    My guest today is Dr. Nirosha Murugan, a Tier II Canada Research Chair in Biophysics and Assistant Professor at Wilfrid Laurier University. Dr. Murugan explores how physics shapes biological processes, with pioneering research into biophotons—ultraweak photon emissions that reveal the hidden interplay between physics, biology, and life.

    By the end of this episode, listeners will understand how biophotons contribute to cellular communication, regeneration, and health. Dr. Murugan’s insights highlight the emerging field of quantum biology and how it connects physics to life, offering transformative potential for medical diagnostics and a deeper understanding of living systems.

    This episode explores the future of medicine through the lens of life’s physical foundations.

    The Murugan Lab https://themuruganlab.com

    Publications https://themuruganlab.com/publications/

    X https://x.com/msahsorin

    Cause of Autism: https://youtu.be/0onzTNYyrmI?si=4cah8YtY8J1dlh0Y

    Autism & Mitochondria: Biophysics meets Biochemistry https://youtu.be/-wXJI719L5s?si=XAMqQ0f1xMDlPqls

    Neurulation, Neuroepitheial Cells, & Mesencephalon https://youtu.be/ZPkb1Fp7EIc?si=OSfUJP9uZIjGe3ZM

    0:00 Dr. Nirosha Murugan

    2:16 Daylight Computer Company, use "autism" for $50 discount

    6:34 Chroma Light Devices, use "autism" for a 10% discount

    9:45 Path into Quantum Biology & Biophysics role on organisms; Bioelectricity

    13:13 Opsins versus Chromophores; Proteins; Photoreceptors & Light

    17:37 The Body Glows & Emits Light (biophotons); Photomultipliers & Measuring Biophotons

    20:37 The Role of Light & Development

    21:04 Seed Germination & Human Development (neurodevelopment) Analogy

    23:54 Environmental Light & Impact on Health; Light Patterns, Spectrums, & Wavelengths

    25:34 Mother's of the original Autistic kids from Leo Kanner

    26:46 Light type exposure & Autism

    29:50 Mitochondria, Light, & Energy

    31:28 Neurocognitive (Dementias) rates & Aging; Reactive Oxygen Species (ROS), Electrons

    35:35 Microtubules & Cell Function; Reverse Engineer Oxidative Phosphorylation- ATPase, Electron Transport Chain & TCA Cycle

    37:14 Cytochrome C Oxidase, Water, Energy, Four Red Light Chromophores- Heme a, a3, CuA, & CuB, vitamin D receptors, Red light & UV Light

    42:11 Tryptophan, Tublin, Microtubules

    46:49 The Role of Water & Energy in Cells

    48:59 Nature's Impact on Health; Get Outside (!), Oxygen

    51:46 Midbrain (mesencephalon), Dopamine, Norepinephrine; Serotonin and Raphe

    53:36 Serotonin & Development (remember the sensory map !)

    55:11 Biophotons & Seasonal changes; Depression, Pale Autistics

    58:02 Cancer & Biophoton Signals

    59:50 Human connection, Biophotons & Quantum Coherence, Energy, & Molecular Signals

    01:01:53 Psychedelics, Depression, Anxiety, Consciousness

    01:05:20 Mitochondria, Memory & Information: What is Information?

    01:09:54 Intersection of Light & Information

    01:12:27 Future Direction in Quantum Biology and Medicine; Silos

    01:13:36 Ryan's journey into Quantum Biology & Practices, Reversing Autoimmune Diseases

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    1 h et 17 min
  • Dr. Kenda Rigdon: The Gut's Microbial Ecosystem, Yeast, Melanin, Birth, & Development
    Aug 18 2025

    My guest today is Dr. Kenda Rigdon. Dr. Rigdon is a microbiologist with a PhD in microbiology and virology from the University of Alabama at Birmingham. Drawing from her expertise, she explores how the gut’s microbial ecosystem—comprising bacteria, yeast like Candida and Malassezia, and other microbes—interacts with genetic and epigenetic factors to influence Autism. Dr. Rigdon highlights the critical role of the birthing process, particularly how vaginal delivery seeds a newborn’s gut with beneficial microbes like lactobacillus, setting the stage for healthy development in the first three years. She also delves into how yeast overgrowth, nutrient competition (e.g., for tryptophan), and environmental factors like manganese and glyphosate exposure can disrupt this delicate ecosystem, potentially exacerbating autism-related symptoms.

    Dr. Rigdon shares insights into the surprising links between melanin, Neanderthal DNA, and Autism. She discusses how specific genetic mutations, such as MTHFR and PAI1, can intersect with Autism. Additionally, she connects melanin production—potentially influenced by gut yeast like Malassezia—to neurological health, drawing parallels with conditions like Parkinson’s. By viewing the gut as a dynamic ecosystem shaped by birth, diet, and early development, this episode offers a fresh perspective on Autism’s microbial roots and practical implications for health, urging listeners to reconsider modern birthing practices and dietary choices in fostering a balanced gut microbiome.

    Dr. Rigdon X https://x.com/KendaRigdon

    Daylight Computer Company

    use "autism" for $25 off at

    https://buy.daylightcomputer.com/RYAN03139

    Chroma Iight Devices

    use "autism" for 10% discount at

    https://getchroma.co/?ref=autism

    0:00 Dr. Kenda Rigdon

    1:14 Journey into Microbiology

    4:08 The Gut's Ecosystem

    8:21 Genetics, Autism, & The Microbial Connection

    13:08 MTHFR & PAI1: Homocysteine, Methionine, Folate

    20:21 The Role of Yeast in Health & Disease; Serotonin, Candida

    26:39 The Fight for Tryptophan

    31:14 Impact of Birthing Method on Gut Health (!)

    33:13 Modern versus Evolutionary Births, Breastfeeding; Oxygen, Acidity, PH

    37:15 Melanin, Cell Protection, Neanderthal DNA, Autism

    40:46 Neuromelanin; Biological Energy, Melanocytes

    43:20 Neanderthal's & Modern Disease & Environments

    47:23 Microbes in the Brain

    53:21 Manganese & Gut Health

    58:22 Gut-Brain Connection & Microbial Balance

    01:03:19 Early Gut Health & Development; Modern Insults

    01:07:21 Future Direction in Gut Health & Kenda's Passion & Love

    X: https://x.com/rps47586

    YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA

    email: info.fromthespectrum@gmail.com

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    1 h et 10 min
  • Relationship of B.2 Strict Schedules & B.3 Fixated Interests: Path, Meaning, & Love
    Aug 4 2025

    For today's episode, we will cover B2 (insistence on sameness, inflexible routines, and ritualized behaviors) and B3 (highly restricted, fixated interests with abnormal intensity). It emphasizes the preference for an internal world, where repetition and self-directed learning thrive, contrasting this with societal misunderstandings that label such behaviors as abnormal. The episode critiques societal pressures to conform to broad knowledge expectations, highlighting how Autistics find comfort in their self-driven focus, supported by neurobiological insights like the role of the mesencephalon in attention and environmental interaction.

    Further, the episode addresses the challenges Autistics face with external disruptions, like unpredictable social interactions or changes to routines, which can feel debilitating due to the brain’s predictive nature and metabolic energy demands. The discussion ties these struggles to the medial prefrontal cortex’s role in adaptive responses, explaining why Autistics may resist environmental changes to maintain their internal homeostasis. The episode underscores the unique learning style of Autistics, advocating for self-directed interests over externally imposed norms.

    Daylight Computer Company

    use "autism" for $25 off at

    https://buy.daylightcomputer.com/RYAN03139

    Chroma Iight Devices

    use "autism" for 10% discount at

    https://getchroma.co/?ref=autism

    00:00 Daylight Computer Company, use "autism" for $25 discount

    02:24 Autism DSM Criteria B, Autism phenotypes, DSM criteria B, restricted repetitive behaviors, focus on B2 and B3, prior episodes (1, 2, 6, 7).

    04:42 B2: Insistence on Sameness, DSM B2, insistence on sameness, inflexible routines, distress at small changes, rigid thinking

    05:24 B3: Fixated Interests and Autistic Intelligence, DSM B3, Kenner/Asperger kids, autistic intelligence, societal mislabeling.

    07:15 Autism and Societal Misunderstandings, Autos (self), societal confusion, discomfort with complexity, Autistics’ comfort in self, internal state shifts.

    09:19 Autistic Learning, Love, & Internal World, Autistic intelligence, learning, repetition, professing, self-directed learning, societal pressure.

    11:40 Path, Meaning, & Love; “Daimon”

    14:42 Neurobiology and Environmental Interaction, Mesencephalon (midbrain), motor movement, sensory integration, attention bias, lack of environmental orientation, social implications, embryogenesis, Autistic resistance to external changes.

    17:34 Chroma Light Devices, use "autism" for 10% discount

    20:43 Routines, Social Challenges, and Adaptive Responses, B2 routines, external insults, brain as prediction machine, metabolic energy, social interactions, Autistic efficiency, frustration with unpredictability, medial prefrontal cortex, adaptive responses

    25:21 Reviews/Ratings & Contact Info

    X: https://x.com/rps47586

    YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA

    email: info.fromthespectrum@gmail.com

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    26 min
  • Part 2: Supplementing Relationships with Self-Directed Communication
    Jul 21 2025

    In this episode, we explore the concept of supplementing relationships in Autism, focusing on the vivid internal dialogues and imaginative "movies" that feel profoundly real. These self-directed monologues and conversations with imagination create a safe, predictable space for social engagement, contrasting with the chaotic external world. We dive into Kanner’s and Asperger’s insights on self-directed speech, used for self-soothing or processing thoughts, not communication. Kanner observed children muttering during solitary play, while Asperger noted lecture-like monologues reflecting autistic intelligence.

    I will share personal experiences of vivid internal dialogues emerging soon after waking, free of external speech issues but disrupted by real-world interactions. These internal relationships, as frequent as an extrovert’s, pose challenges when balancing with social expectations, offering a predictable haven for exploring restricted interests

    Supplementing Relationships with Visual Thinking https://youtu.be/lglEGQ7pSlc?si=TgwuMMFGRPmAcCwk

    Daylight Computer Company

    use "autism" for $25 off at

    https://buy.daylightcomputer.com/RYAN03139

    Chroma Iight Devices

    use "autism" for 10% discount at

    https://getchroma.co/?ref=autism

    0:00 Chroma Light Devices, use "autism" for 10% discount

    03:11 Supplementing Relationships and Autism: Supplementing relationships, autism, internal dialogue, monologue, imagination, vivid movies, real-like, accelerator.

    04:14 Historical Context of Autism Start Time: Autism history, autos, self, dreamlike states, Eugen Bleuler, 1900s, schizophrenia, late 1950s.

    05:14 Shared Phenotypes and Kanner/Asperger Contributions: Autism, schizophrenia, phenotypes, speech, language, motor control, intensity, Kanner, Asperger, self-directed communication.

    05:55 Autism, Isolation, and Speech/Language Challenges: Isolation, chaotic world, speech issues, language issues, biology, socialness, negative experiences.

    07:12 Kanner’s Observations on Self-Directed Speech: Kanner, self-directed speech, internal needs, self-soothing, narrating thoughts, solitary play, no listener, repetitive activities.

    09:33 Asperger’s Insights on Monologues and Autistic Intelligence: Asperger, monologues, obsessions, academic style, self-satisfaction, autistic intelligence, accelerated learning, solitary activities.

    12:23 Personal Experience with Internal Dialogues and Disruptions: Personal experience, internal dialogues, vivid movies, waking fixation, motor movements, silent speaking, listening dissonance, medial prefrontal cortex.

    15:00 Internal Socialness, Supplementing Relationships, and Real-World Challenges: Internal socialness, extrovert comparison, no speech issues, supplementing relationships, vivid imagination, real-world social challenges, predictability, restricted interests, early memories.

    19:08 Reviews/Ratings & Contact Info

    19:50 Daylight Computer Company, use "autism" for $25 discount

    X: https://x.com/rps47586

    YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA

    email: info.fromthespectrum@gmail.com

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    24 min
  • Samantha Fox: M.A., CCC-SLP, S2C: Autism, Apraxia, & Spelling 2 Communicate
    Jul 14 2025

    My guest today is Samantha Fox. Sam is a Speech-Language Pathologist with a Master’s from Kent State University and the founder of, Beyond Speech Therapy Center, where they focus on personalized therapy and building meaningful connections with clients. As a registered Spelling to Communicate practitioner with deep expertise in Early Intervention, Sam brings a unique perspective to supporting non-speaking and minimally speaking individuals with Autism, Apraxia, and speech sound disorders. Today’s episode is all about Speech-Language Pathology and Spelling to Communicate interventions. By the end, you’ll have a deeper understanding of these powerful protocols.

    Sam Fox https://www.beyondspeechtherapycenter.com/our-team

    Beyond Speech Therapy Center https://www.beyondspeechtherapycenter.com/home

    Facebook https://www.facebook.com/BeyondSpeech

    I-ASC https://i-asc.org

    Other episodes:

    Dr. Reza Shadmehr: Computational Motor Control & The Cerebellum https://youtu.be/LoklISzlXK8?si=AoVKbHRZ0hDDtdY0

    Katie Asher: Understanding Communication, Telepathy, and Spiritual Existence https://youtu.be/7FJ52cyfShg?si=gmf7PxrCajcXHkUS

    Daylight Computer Company

    use "autism" for $25 off at

    https://buy.daylightcomputer.com/RYAN03139

    Chroma Iight Devices

    use "autism" for 10% discount at

    https://getchroma.co/?ref=autism

    0:00 Sam Fox

    2:15 Learning about Spellers; Kaden

    8:55 Beyond Speech Therapy Center; Spelling 2 Communicate; I-ASC

    18:06 Non-Verbal, Motor Control, Apraxia, & Communication

    23:03 Presuming Competence in Non Speaking Individuals

    31:10 Impact of Communication on Behavior; The use of Spelling; Self-Injurious Behaviors

    40:08 Understanding Apraxia

    43:56 The Process of Spelling 2 Communicate

    50:40 Building Motor Skills for Communication

    57:27 Overcoming Barriers in Spelling

    1:02:29 The Importance of Consistency, Practice, Reasonable Expectations & Patience; Insurance Coverage

    1:11:58 The Leap of Faith in Spelling

    1:16:56 The Future of Spelling 2 Communicate

    X: https://x.com/rps47586

    YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA

    email: info.fromthespectrum@gmail.com

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    1 h et 18 min