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The 2026 Update: Navigating the New Medication Fact Book for Psychiatric Practice

The 2026 Update: Navigating the New Medication Fact Book for Psychiatric Practice

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Are you a busy clinician looking for bottom-line assessments of the latest psychiatric medications? In this episode, we dive into the Eighth Edition of the Medication Fact Book for Psychiatric Practice. Authored by Talia Puzantian, PharmD, and Daniel J. Carlat, MD, this comprehensive 2026 update is designed to provide "need-to-know" information that can be quickly absorbed during a busy day of seeing patients.

Join us as we explore the latest additions to this essential reference guide, including:

  • New FDA Approvals: We cover nine new fact sheets featuring recently approved treatments, such as the novel antipsychotic xanomeline/trospium (Cobenfy), the rapid-acting postpartum depression drug zuranolone (Zurzuvae), and the new antidepressant gepirone (Exxua).
  • Clinical Decision Tools: Learn about the book's 11 updated treatment algorithms and 33 quick-scan tables, covering everything from ADHD and mood stabilizers to somatic treatments like blue light blocking glasses.
  • Practical Practice Management: We discuss a brand-new appendix dedicated to navigating the frustration of prior authorization requests and denials, alongside updated guidance on dosing in hepatic and renal impairment.
  • Expanded Treatment Categories: Discover the latest protocols for anti-amyloid monoclonal antibodies in dementia care and updated strategies for managing side effects like weight gain and tardive dyskinesia.

Whether you are a psychiatrist, nurse practitioner, or psychologist, this episode offers a preview of the algorithms and clinical pearls you need to streamline your prescribing practice.

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