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One in Six Billion

One in Six Billion

Auteur(s): Andrew Hattersley and Maggie Shepherd
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A podcast about diabetes and genes hosted by Andrew Hattersley and Maggie Shepherd.

© 2025 One in Six Billion Hygiène et mode de vie sain Troubles et maladies
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  • Series 4 Episode 8. Rohini Bajekal and Shivani Misra. The challenge of diagnosing monogenic diabetes in South Asians

    Series 4 Episode 8. Rohini Bajekal and Shivani Misra. The challenge of diagnosing monogenic diabetes in South Asians
    Oct 14 2025

    Rohini Bajekal describes how she had years of receiving inappropriate lifestyle advice before Glucokinase MODY was diagnosed. Dr Shivani Misra’s research has shown that failure to diagnose monogenic diabetes is even common in South Asians than in the white European population.

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    36 min
  • Series 4 episode 7. Sarah Richardson. Small extra-islet beta cells matter

    Series 4 episode 7. Sarah Richardson. Small extra-islet beta cells matter
    Sep 30 2025

    Sarah Richardson talks about her new exciting research on insulin producing beta-cells that are single cells or small clusters rather than in islets. These extra-islet beta-cells make up most of the insulin producing capacity of the pancreas in young children and are particularly susceptible to immune attack in Type 1 diabetes. This important research explains why the loss of insulin producing cells in Type 1 diabetes is more severe in young children and informs future work on treating and preventing Type 1 diabetes.

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    21 min
  • Series 4 episode 6: Hannah Robinson and Nick Thomas. Taking immunotherapy to delay adult-onset Type 1 diabetes

    Series 4 episode 6: Hannah Robinson and Nick Thomas. Taking immunotherapy to delay adult-onset Type 1 diabetes
    Sep 16 2025

    Hannah Robinson was the first adult in the UK to be given the new immunotherapy drug Teplizumab, which aims to slow down the development of type 1 diabetes. Hannah had multiple pancreatic autoantibodies and hence is on the path to developing Type 1 diabetes (Series 4 Episode 3). Her consultant, Nick Thomas, arranged 14 consecutive daily hospital visits for her to receive the drug through a drip.

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    19 min
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