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Traumatic brain injury can change everything. Not just how the brain functions, but how a person understands themselves, their limits, and their future.

In this episode of Rupture: The World of BestGuessistan, host Wendy Lurrie is joined by neuro-ophthalmologist Dr. Melody Merati for an honest, deeply human conversation about what TBI really looks like beyond the MRI.

They discuss why traumatic brain injury recovery is rarely linear, why many symptoms never appear on scans, and why patients so often feel dismissed or blamed when healing takes longer than expected. From dizziness and headaches to emotional volatility, sensory overload, and identity shifts, this episode explains the wide range of TBI symptoms and why no two recoveries look the same.

Dr. Merati also addresses the urgent need for patient advocacy and systemic change. From the shortage of neurologists to the spread of misinformation about treatments, the conversation highlights the gaps in care that leave many brain injury survivors navigating recovery alone.

At its core, this episode is about acceptance. Not as resignation, but as a necessary step toward building a meaningful life after rupture.

If you are living with traumatic brain injury, caring for someone with TBI, or trying to understand invisible disability, this episode offers clarity, validation, and language for what you may be experiencing.

Watch the full episode on YouTube: https://www.youtube.com/@BestGuessistan

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What happens when the systems designed to support people stop working?

In this episode of Rupture: The World of BestGuessistan, strategic HR executive Marlo Green joins the conversation to unpack why modern HR leadership is failing employees. And how it can be rebuilt.

Marlo shares her journey into HR, the limits of policy-driven people operations, and why psychological safety, trust, and manager capability are the real drivers of employee engagement. Together, we explore moments of rupture at work. Those breaking points that reveal whether workplace cultures are truly humane or merely performative.

This episode is essential listening for HR leaders, managers, founders, and anyone responsible for shaping the employee experience.

Watch the full episode on YouTube: https://www.youtube.com/@BestGuessistan

Subscribe to our Substack: https://bestguessistan.substack.com/

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Menopause is not just hot flashes. It is a full body and brain shift that collides with modern work, leadership expectations, and a culture that still treats the topic as taboo.

Wendy Lurrie sits down with leadership coach and brand consultant Lauren Glazer to talk about the real workplace impact of perimenopause. They unpack why so many women learn what’s happening from friends, not doctors. Why identity can be the first system to fail. And what simple workplace signals and accommodations can change everything.

They also explore the “operating system update” metaphor, the brain’s remodeling across puberty, pregnancy, and perimenopause, and the role allies can play, including the men who want to better understand what’s happening at home and at work.

If you are navigating symptoms, supporting a partner, leading a team, or working in HR, this episode is a practical and human place to start.

Watch the full episode on YouTube: https://www.youtube.com/@BestGuessistan

Subscribe to our Substack: https://bestguessistan.substack.com/

Follow us on Instagram: https://www.instagram.com/bestguessistan/

Join the conversation on Facebook: https://www.facebook.com/bestguessistan/