What does the future of weight loss and obesity care really look like?

In this special annual predictions episode of the Pound of Cure Weight Loss Podcast, Dr. Matthew Weiner, registered dietitian Zoë, and Deidre review their 2025 weight loss predictions and share bold, evidence-based predictions for 2026.

They break down what’s coming next in GLP-1 medications, including pricing, insurance coverage, injectable vs oral GLP-1s, and how medications will increasingly be combined with nutrition, lifestyle changes, and bariatric surgery. The episode also explores major shifts in nutrition trends, including why protein quality will matter more than quantity, why fiber may be the next big focus, and how whole-food diets outperform processed “GLP-1 support” products.

You’ll also hear forward-looking conversations about:
• AI-powered meal planning and obesity care
• Personalized nutrition tools and body composition tracking
• Maintenance-phase weight loss becoming its own specialty
• The future role of bariatric surgery alongside GLP-1 medications
• Why sustainable habits matter more than ever

This episode is ideal for anyone using or considering GLP-1 medications, navigating insurance coverage, or looking for realistic, long-term weight loss strategies grounded in science—not trends.

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In this powerful patient interview, Ray and Lisa open up about more than 25 years of weight management struggles, even while “eating like a mouse” and strictly following traditional dieting guidelines. They describe the emotional toll of feeling like their bodies were working against them—until they finally learned about food noise, the brain-driven hunger signals that make portion control and willpower-based dieting nearly impossible.

Guided by their PCP and cardiologist, they began a GLP-1 medication and immediately discovered that their challenges weren’t due to lack of discipline but physiology. They explain how GLP-1 therapy helped quiet food noise, curb impulse eating, and make portion control feel natural for the first time in decades.

But their transformation didn’t come from medication alone. Ray and Lisa share how combining GLP-1s with consistent strength training, intentional daily movement, balanced nutrition, and sustainable habits led to life-changing results — from better cholesterol and blood pressure to increased stability, stamina, and the ability to fully engage with their grandchildren again.

Their story is a relatable, inspiring roadmap for anyone navigating weight loss after 40, metabolic changes, thyroid issues, menopause, emotional eating, or long-term dieting frustration. This episode highlights the science behind food noise, the importance of muscle maintenance on GLP-1s, and why a whole-body, personalized approach creates lasting change.

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In this episode of the Pound of Cure Weight Loss Podcast, Dr. Matthew Weiner breaks down the surprising connection between gastric bypass surgery and alcohol metabolism. You’ll learn why a single drink can hit harder post-op, how the altered digestive system impacts blood alcohol levels, and what this means for addiction risk after surgery. If you’ve had bariatric surgery—or work with patients who have—this episode offers must-know insights into post-surgery physiology, safety, and long-term success.

Whether you’re questioning if you can still enjoy alcohol or are concerned about the risk of transfer addiction, Dr. Weiner separates myth from fact in a way only he can.

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