Rachel Maddow hosts former Vice President Kamala Harris, the 2024 Democratic nominiee for president, on the eve of the publication of her new book, "107 Days," to revisit some of the decisions and circumstances that shaped the 2024 election, and to discuss politics and activism in the second Trump term.

Rachel shares her impressions of the interview with Lawrence O'Donnell at the end of the hour.

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Rachel Maddow points out that Donald Trump is following the "strongman" playbook so closely, and with such a lack of originality, that his behavior in his second term has become entirely predictable. And yet, for all of his aspirations to be a strongman, his leadership suffers from some profound weaknesses, from the economy to healthcare to criminal justice to immigration.

Rachel Maddow talks with Jonathan Mahler, staff writer for the New York Times Magazine, about his reporting on the concerted effort by the Trump administration to destroy America's global leadership in cancer research. What constituency supports Donald Trump sabotaging work that not only saves lives but supports countless American jobs?

Former CDC director Susan Monarez is set to testify before the Senate this week as HHS Secretary Robert F. Kennedy is stacking the vaccine advisory board with vaccine skeptics.

And the Trump administration claimed to have burned a massive quanitity of contraceptives meant to be distributed in developing countries, with the false explanation that the contraceptives are abortifacients, only for it to be discovered that the contraceptives are still sitting in storage.

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The estate of Jeffrey Epstein released materials today to the House Oversight Committee, including the "birthday book" that Donald Trump disputed (and continues to dispute) includes a crude drawing and note he submitted with his signature. Rachel Maddow looks at this and other new revelations and how much energy Trump is putting into denying what seems plain about Trump's role in a disgusting scandal of historic scale.

Donald Trump's poor choice of Robert F. Kennedy Jr. as his HHS secretary has cost him a leadership role in public health as Kennedy dismantles key departments and agencies, cuts funding and fires experts, leaving state leaders to take charge of vaccine availability and other health issues. Dr. Tao Sheng Kwan-Gett, chief science officer for the Washington State Department of Health, joins Rachel Maddow to discuss.

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