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The hidden story of endometriosis: Pain, lesions, and the microbiome

The hidden story of endometriosis: Pain, lesions, and the microbiome

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If you’ve been diagnosed with endometriosis, the big question is: What type of lesions?

In this episode, Lara challenges long-held assumptions to explore:

  • the three types of endometriosis lesions,
  • emerging evidence that superficial lesions may not explain pain or other symptoms,
  • alternative explanations for pelvic pain and infertility, including pelvic congestion, immune dysfunction, and gut microbiome imbalance, and
  • an update on the bacterial contamination hypothesis.

Links:

  • Could pelvic congestion syndrome explain your pelvic pain?
  • Prevalence of endometriosis in asymptomatic women (1991 study)
  • Surgical removal of superficial peritoneal endometriosis for managing women with chronic pelvic pain: time for a rethink? (2019 BJOG article)
  • Bacterial contamination hypothesis (2018 paper)
  • Fusobacterium infection facilitates the development of endometriosis (2023 paper)
  • ANZCA 2024 Statement on pelvic pain and endometriosis

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