Épisodes

  • Robin Hanson - Civilizational Goals to Prevent Decline
    Nov 16 2025
    On Sunday, November 16, 2025, at 1 p.m. U.S. Pacific Time, the U.S. Transhumanist Party invites Robin Hanson to continue the discussion on cultural drift and how civilizational decline can be prevented by positing grand unifying goals that a society can unite around. The discussion will address the feasibility of a unifying goal such as radical life extension, which could be framed in objectively measurable ways, with specific incremental goalposts. It will also delve into the challenge of how to get from the current highly turbulent and polarized political and cultural situation to one in which large segments of society embrace the grand goal and work toward it.
    In addition, the discussion will aim to address various viewer questions and observations from the previous Virtual Enlightenment Salon with Robin Hanson of August 25, 2024: https://www.youtube.com/watch?v=po99ApM8T7s
    Robin Hanson is an Associate Professor of Economics at George Mason University, and received his Ph.D in 1997 in social sciences from Caltech. He joined George Mason's economics faculty in 1999 after completing a two-year post-doc at U.C Berkeley. His major fields of interest include health policy, regulation, and formal political theory. He is also interested in all aspects of the future, including uploading, nanotech, cosmology and the foundations of physics, future economic growth rates, limits of computation, and the origin of life.
    Read Robin Hanson’s writings on his website, Overcoming Bias: https://www.overcomingbias.com/
    See Robin Hanson’s home page at George Mason University: http://mason.gmu.edu/~rhanson/home.html
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    1 h et 56 min
  • TransVision Madrid 2025 Summit: Blasco, Magalhães, Crespo-Barrios, Muñoz-Espín, Coles, Hartenstein
    Nov 9 2025
    On Sunday, November 9, 2025, at 1 p.m. U.S. Pacific Time, watch the stream of six presentations from the TransVision Madrid 2025 International Longevity Summit from six distinguished researchers in various aspects of the fight against aging, as well as a question-and-answer session. These presentations transpired on International Longevity Day, October 1, 2025.
    The presentations included in this compilation stream include the following:
    - Maria Blasco, Director of CNIO, Spain’s National Cancer Research Center, presented on telomere shortening and the enzyme telomerase.
    - João Pedro de Magalhães, Chair of Molecular Biogerontology at the University of Birmingham, Chief Science Officer of YouthBio Therapeutics, presented on the subject of “The Science of Ageing and the Future of Longevity”.
    - José Crespo-Barrios, CEO of Regeneratics, presented on anti-atherogenics, angioregenerative therapies, and possible applications for treating COVID and Long COVID. He invited Dr. Israel Pichardo-Casas, Chief Scientific Officer of Legacy Lyfe Labs LLC to also give a brief virtual presentation, entitled “Validating the AI Model to Test Biologics as Therapeutic Targets”.
    - Daniel Muñoz-Espín, Professor and Group Leader in Cancer Early Detection at the University of Cambridge, discussed the role of senescence in lung cancer and aging, as well as novel senotherapeutic and detection tools, and also discussed transient reprogramming as an antitumorigenic therapy.
    - Natalie Coles, Director of Supercentenarian Research at the LEV Foundation, discussed her work in sampling biological data of supercentenarians, highlighting the case of Maria Branyas (1907-2024), who had been the world’s oldest woman from January 17, 2023, until August 19, 2024.
    - Lars Hartenstein of McKinsey Health Institute provided a presentation on “Longevity and Healthier Cities – Madrid”, discussing possible contributing factors to Madrid having become the world’s most longevous city.
    The U.S. Transhumanist Party thanks TransVision Madrid and its fellow transhumanist political party in Spain, Alianza Futurista, for providing the means to offer these presentations to our audience.
    Visit the website of TransVision Madrid: https://www.transvisionmadrid.com/
    Visit the website of Alianza Futurista: https://www.alianzafuturista.com/
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    1 h et 54 min
  • Nicolás Cherñavsky & Nina Torres Zanvettor
    Nov 2 2025
    On Sunday, November 2, 2025, at 1 p.m. U.S. Pacific Time, the U.S. Transhumanist Party invites Nicolás Cherñavsky and Nina Torres Zanvettor of the Rejuvenation Science Institute to discuss their efforts in seeking to replicate the rat rejuvenation experiment of Harold Katcher, in which the researchers extracted small extracellular vesicles from the blood of young pigs and injected them into old Sprague-Dawley rats, reporting that they managed to rejuvenate the animals according to a series of parameters, including memory, grip strength, blood markers, senescent cells, and others. Harold Katcher’s experiment led to a world record in rat longevity, as Sima the rat reached the age of 1464 days (over 4 years).
    The Rejuvenation Science Institute has the mission of carrying out and promoting scientific research in the field of rejuvenation, longevity, and aging. Its ultimate goal is to develop rejuvenation therapies to eliminate the limit that aging imposes on human lifespan and prevent the age-related diseases, such as cardiovascular diseases, cancer and Alzheimer's disease, which kill 110,000 people worldwide every day.
    Visit the website of the Rejuvenation Science Institute at https://www.rejuvenescimento.org/english.
    Read the May 1, 2025, study from the Rejuvenation Science Institute, “Feasibility of intravenous injection of pig plasma extracellular particles into rats: an acute study” - https://www.journals.tmkarpinski.com/index.php/ejbr/article/view/772
    Citation: Cherñavsky, N.; C. de Campos Zani, S.; A. Mori, M.; Torres Zanvettor, N. Feasibility of Intravenous Injection of Pig Plasma Extracellular Particles into Rats: An Acute Study. European Journal of Biological Research 2025, 15, 50-57.
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    1 h et 56 min
  • TransVision Madrid 2025 Summit: Longevity March, Omniscope, Gil Rodas, Steve Horvath, Michael Ringel
    Oct 26 2025
    On Sunday, October 26, 2025, at 1 p.m. U.S. Pacific Time, watch a stream of notable events that transpired in Madrid, Spain, on October 1, 2025, International Longevity Day, including the March for Longevity and presentations of various approaches in the fight against aging and disease by Vijay Vaswani, Holger Heyn, Gil Rodas, Steve Horvath, and Michael Ringel.
    The stream begins with the March for Longevity that took place in Madrid on International Longevity Day, October 1, 2025. The march took participants through some of the main streets and plazas of Madrid and ended in front of Madrid City Hall, all the while a battle against the Grim Reaper was waged.
    Footage of the march includes remarks by José Luis Cordeiro, organizer of the TransVision Madrid 2025 International Longevity Summit, and Juan Llopis Climent, Secretary of Alianza Futurista, the transhumanist political party in Spain.
    The stream continues with a session from Day 1 of the TransVision Madrid 2025 Summit, entitled “The Cellular Model of Age: Decoding Healthspan through Exercise, Immunology, and Epigenetics”, featuring detailed presentations by Vijay Vaswani and Holger Heyn, co-founders of Omniscope; Dr. Gil Rodas – the medical doctor for the FC Barcelona soccer club, who, in his presentation entitled “Integrating Deep Immune Profiling in Modern Football Medicine”, discussed insights regarding longevity in athletes and why athletes tend to live longer than the general population; and Dr. Steve Horvath of Altos Labs, who, in his presentation on “Epigenetic Clocks, Immunity, and Interventions”, provided an overview of his famous studies regarding aging clocks and which medical treatments and lifestyle approaches do and do not affect aging at the epigenetic level.
    Dr. Michael Ringel of Life Biosciences then delivered a presentation entitled “Partial Epigenetic Reprogramming to Reverse Age-Related Diseases” to discuss both the theory behind partial epigenetic reprogramming and some of its proximate applications.
    The U.S. Transhumanist Party thanks TransVision Madrid and its fellow transhumanist political party in Spain, Alianza Futurista, for providing the means to offer these presentations to our audience. In particular, we thank Sergio Tarrero of Alianza Futurista for the edited videos pertaining to the March for Longevity and the presentations from Omniscope and Dr. Gil Rodas.
    Visit the website of TransVision Madrid: https://www.transvisionmadrid.com/
    Visit the website of Alianza Futurista: https://www.alianzafuturista.com/
    Visit the website of Omniscope: https://www.omniscope.ai/
    Visit the website of Altos Labs: https://www.altoslabs.com/
    Visit the website of Life Biosciences: https://www.lifebiosciences.com/
    Watch the U.S. Transhumanist Party’s previous stream of TransVision Madrid presentations from Jose Cordeiro, Aubrey de Grey, and David Wood: https://www.youtube.com/watch?v=MV6njT849XI
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    1 h et 56 min
  • Andreas Xirtus on the Idea of Singularity
    Oct 19 2025
    On Sunday, October 19, 2025, at 1 p.m. U.S. Pacific Time, the U.S. Transhumanist Party invites Andreas Xirtus to discuss the concept of singularity and its various possible meanings and significances.
    Andreas Xirtus is a popular podcaster with a large following; he is the founder of a historical restoration society known as Tartary Nova and Director of the Fediverse, a free software foundation creating tools to protect free speech. He has studied nanotechnology and worked as a nanotechnology engineer and microsatellite specialist for NASA, a social-media strategist for Turner Entertainment, and a content creator at Timcast Media.
    Watch the previous U.S. Transhumanist Party Virtual Enlightenment Salon with Andreas Xirtus of December 3, 2023: https://www.youtube.com/watch?v=gbwf_ZwchVI
    Visit Andreas Xirtus’s YouTube channel: https://www.youtube.com/@xirtus
    Visit Andreas Xirtus’s website: https://andreas.me/ - and see his resume: https://andreas.me/resume.html
    Watch Andreas Xirtus’s previous interviews with USTP Chairman Gennady Stolyarov II from 2021 - https://www.youtube.com/watch?v=DdGVleMnPFE – 2023 – https://www.youtube.com/watch?v=7ifx55wo7fQ – and 2025 – https://www.youtube.com/watch?v=gX9nNBVayXM.
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    1 h et 55 min
  • TransVision Madrid 2025 Summit
    Oct 12 2025
    On Sunday, October 12, 2025, at 1 p.m. U.S. Pacific Time, watch a stream of presentations on longevity investment, public advocacy, and the potential for gene therapies to achieve breakthroughs in curing diseases and reversing biological aging, delivered during Day 2 of the TransVision Madrid 2025 International Longevity Summit on October 2, 2025, featuring Angel Versetti, Liz Parrish, Sergio Tarrero, Mariana De Chellis, Cody Dean, Carmen Simón Mateo, Clara Fernández Porta, and Carlos Díez-Ruza.
    The U.S. Transhumanist Party is pleased to bring you these thought-provoking presentations as its October 12 Virtual Enlightenment Salon. The featured portions of the TransVision Madrid 2025 conference in this stream are the following:
    - Angel Versetti (Longevity Venture Builder / Versetti Family Office): “Some Candid Raw Thoughts on the State of Longevity as an Investment”
    - The Panel on Public Longevity Advocacy
    Moderator: Sabinije von Gaffke
    Speakers: Carmen Simón Mateo (Apadrina la Ciencia), Sergio Tarrero (Alianza Futurista), Clara Fernández Porta (Progevita), Carlos Díez-Ruza (Madrid e-Health Cluster), Mariana De Chellis (Coalition for Radical Life Extension), Cody Dean (Inmortalis/Neovia)
    - Liz Parrish (Founder and CEO of BioViva, U.S. Transhumanist Party Advocacy Advisor and 2020 U.S. Vice-Presidential Candidate): “BioViva and the Evolution of Gene Therapy: Where We Have Been and Where We Are Going”
    The U.S. Transhumanist Party thanks TransVision Madrid and its fellow transhumanist political party in Spain, Alianza Futurista, for providing the means to offer these presentations to our audience.
    Visit the website of TransVision Madrid: https://www.transvisionmadrid.com/
    Visit the website of Alianza Futurista: https://www.alianzafuturista.com/
    Visit the website of BioViva: https://bioviva-science.com/
    Visit the website of the Coalition for Radical Life Extension: https://www.rlecoalition.com/
    Visit the website of Immortalis: https://joinimmortalis.com/
    Watch the U.S. Transhumanist Party’s previous stream of TransVision Madrid presentations from Jose Cordeiro, Aubrey de Grey, and David Wood: https://www.youtube.com/watch?v=MV6njT849XI
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    1 h et 58 min
  • TransVision Madrid 2025 Summit - Presentations by Jose Cordeiro, Aubrey de Grey, and David Wood
    Oct 5 2025
    On Sunday, October 5, 2025, at 1 p.m. U.S. Pacific Time, watch the presentations from Dr. Jose Cordeiro, David Wood, and Dr. Aubrey de Grey, that were delivered during Day 2 of the TransVision Madrid 2025 International Longevity Summit on October 2, 2025. From Madrid, Spain, the U.S. Transhumanist Party is pleased to stream to you these in-depth presentations by three of the leading transhumanist thinkers.
    Dr. Jose Cordeiro provided an overview of the TransVision Madrid conference, the role of Spain in advancing healthy longevity, and how the history and trajectory of technological advances can bring about “Vita Plus Ultra” – “life far beyond” current limits.
    Dr. Aubrey de Grey provided a presentation entitled “Where do we stand?” – highlighting the current status of the quest to reverse biological aging through the damage-repair approach, including key insights from the Robust Mouse Rejuvenation Study #1 (RMR1) and the major objectives of the RMR2 study for which the pilots are now underway.
    David Wood presented on the Longevity Dividend and the Longevity Dividend Paradox – why correct arguments about the massive economic benefits of greatly extended longevity have not yet led to significant political support for rejuvenation research – and how that paradox might be overcome.
    The U.S. Transhumanist Party thanks TransVision Madrid and its fellow transhumanist political party in Spain, Alianza Futurista, for providing the means to offer these presentations to our audience.
    Visit the website of TransVision Madrid: https://www.transvisionmadrid.com/
    Visit the website of the Longevity Escape Velocity Foundation (LEVF): https://levf.org
    Watch the previous Virtual Enlightenment Salons with Jose Cordeiro, David Wood, and Aubrey de Grey:
    - Jose Cordeiro (September 20, 2020) – https://www.youtube.com/watch?v=kmF-6ftCm3U
    - Aubrey de Grey (February 21, 2021) – https://www.youtube.com/watch?v=ohet4kAfskM
    - David Wood on “Vital Foresight” (July 18, 2021) – https://www.youtube.com/watch?v=q9Aj7Z6qcnM
    - David Wood on the Transhumanist Shadow (January 2, 2022) – https://www.youtube.com/watch?v=GPbijrxUm3o
    - Aubrey de Grey on Robust Mouse Rejuvenation (February 19, 2023) – https://www.youtube.com/watch?v=xx45Z9eRLb8&t=2s
    - Jose Cordeiro and David Wood on “The Death of Death” (June 25, 2023) –https://www.youtube.com/watch?v=zf6SXx_VNis
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    1 h et 56 min
  • The Progress of Artificial Intelligence and Why Humans Will Not Be Made Obsolete Anytime Soon
    Sep 28 2025
    On Sunday, September 28, 2025, at 1 p.m. U.S. Pacific Time, watch the presentation by Gennady Stolyarov II, Chairman of the U.S. Transhumanist Party, which offers a balanced portrayal of areas in which artificial intelligence has made impressive strides recently, and areas where humans will remain superior or uniquely capable for a long time. Countering both the hype and fear surrounding artificial intelligence, Chairman Stolyarov’s remarks encourage us to harness the beneficial applications of AI while recognizing the enduring advantages of our humanity.
    This presentation was originally delivered virtually at the Vanguard Scientific Instruments in Management 2025 (VSIM-2025) conference in Ravda, Bulgaria, on September 9, 2025. The recording includes introductory remarks by Professor Angel Marchev Sr. and discussion in the subsequent Q&A session, with comments by Anton Kulaga and David Wood.
    References
    VSIM-2025 Conference Website: https://vsim-conf.info/
    “AI’s Achilles Heel—Puzzles Humans Solve in Seconds Often Defy Machines” by Deni Ellis Bechard. Scientific American. July 18, 2025 - https://www.scientificamerican.com/article/tests-that-ais-often-fail-and-humans-ace-could-pave-the-way-for-artificial/
    Three sets of ARC-AGI problems available for humans to try: https://arcprize.org/arc-agi
    François Chollet, "On the Measure of Intelligence" (2019) - https://arxiv.org/abs/1911.01547
    U.S. Transhumanist Party Virtual Enlightenment Salon with Peter Voss on the Path to AGI – August 4, 2024 – https://www.youtube.com/watch?v=ZJm-z28vIoc
    U.S. Transhumanist Party Virtual Enlightenment Salon with Rafi Qumsieh – September 7, 2025 –https://www.youtube.com/watch?v=ExLfEPvg1-0
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    1 h et 7 min