Mike Blue is the CEO of HistoSonics. The company recently developed a device that uses ultrasound to destroy tumors.

On today’s show, Mike talks about how a garage-built prototype became an FDA-approved machine; changing the company’s story after a failed clinical trial; and why he loves being a salesman but hates most sales pitches.

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Chris Urmson is the co-founder and CEO of Aurora, a company trying to bring autonomous driving to commercial trucking.

Chris led a team at the 2004 DARPA challenge that launched the autonomous vehicle industry. Then he held a senior role at Google’s self-driving car project, which later became Waymo.

On the show today, he talks about the long arc of autonomous driving, why he left Google, and the future of autonomous trucking.

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Michael Porter is the Chief Technology Officer of OceanWell.

Michael's problem is this: How can you desalinate water at the bottom of the ocean – and deliver it to land at a cost that’s competitive with other sources of fresh water?

On today’s show, Michael explains how he built OceanWell’s prototype in his kitchen, what it takes to make a system that’s less disruptive to marine life, and why innovations from the oil and gas industry are making his work possible.

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