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Holmes investigates a major industry and finds there is more to smoke than meets the eye. Orlando Pearson, Watson's successor as the assistant of Sherlock Holmes, was entrusted by the doctor with notes on cases too controversial to publish at the time.

Holmes meets Joseph Haydn in London and the two form an instant bond. This encounter and a later one with Haydn's young acquaintance, Beethoven, assume a new importance when Holmes and Watson travel to Vienna on a diplomatic mission and are consulted by Constanze Mozart, widow of Wolfgang Amadeus Mozart.

Holmes is charged by the permanent special adviser to the prime minister, his brother Mycroft, to plot a new course for Great Britain following the country's vote in a plebiscite to secede from the Entente Cordiale. Holmes demonstrates that politics truly is an art and that all things are possible as he travels to Washington, Moscow, and Paris meeting statesmen who bear no resemblance at all to the present-day holders of the equivalent posts.

Can you prove anything from statistics on death rates? On the train back to London after solving the case of the stockbroker's clerk, Holmes asks some extremely penetrating questions about Dr. Watson's medical practice in Paddington and that of Dr. Anstruther next door. The questioning is inconclusive, but the questions suddenly become relevant when official investigations are launched into death rates in Paddington and Watson is fortunate that Holmes is on hand.

Why does Irene Adler, mistress of newspaper tycoon, Robert Munroe, lock herself into a cupboard several times a day? The antipodean magnate wants to know. And why is former Prime Minister, Charles Sedgefield, causing delays to the publication of a report on a recent Middle East war? As a representative of the British government, Mycroft wants to know.

Soon after Holmes's return from apparent death, Holmes and Watson return from a walk through London and find a preacher waiting for them. He wants their help in writing his account of the life of a religious leader in an Eastern Mediterranean country whose death has caused unparalleled speculation.

In May 1941, Hitler's Deputy, Rudolf Heβ flew solo to Great Britain. The reason for his flight remained a mystery throughout the rest of the War as he brought no new peace proposals, provided no new insight into Hitler's plans, and did not claim political asylum. In May 1945 and with the war almost at an end, the British Government must decide whether to send the frequently overwrought Heβ back to Germany to face trial on war crimes charges.

Is the London Softwear Company going to close its London factory? Ambitious politician Mr. Lawler, who has commissioned Sherlock Holmes in two previous cases, wants Holmes to find out. And what is the company's special Dutch finishing process, and why does London Software Company's managing director spend so much time in Amsterdam? In a variety of disguises, Holmes and Watson find out the true meaning of a Dutch Sandwich.

Holmes is petitioned by the groom of the Bedlam lunatic asylum to investigate a couple who have appeared at his stables. And after the notorious winter of 1894-5, the politician Mr. Lawler, previously encountered in The Minister and the Moguls, gives Holmes a commission to investigate whether the climate is changing and whether industrialization is the cause.

Prime Minister, Herbert Asquith, and Inspector Gregson, long out of touch with Sherlock Holmes, meet the great detective on 28 June 1914, the day of the assassination of Archduke Ferdinand in Sarajevo. The Germans have introduced a new code and it has baffled the British secret service. As international tensions increase and more messages in the new code are intercepted, the urgency to decrypt mounts, but Holmes is preoccupied with the events that form the narrative of His Last Bow.

Holmes and Watson at the darkest place on earth in April 1945.

In the early days of their collaboration, Dr Watson assessed Sherlock Holmes’s knowledge of chemistry as profound. It is thus hardly surprising that German chemist and future noble prize winner, Fritz Haber, should approach the Great Baker Street detective, for help on a new and transformative industrial process that he is trying to make viable. But, as the first World War breaks out, was there more to the process than met the eye?

Unearthed after being lost for nearly a century, at last the memoirs of Mycroft Holmes are available to the general public. In this volume we see what it is when one extraordinarily talented person is the British Government as Mycroft Holmes applies his skills in statecraft to tax evasion, royal honors, Partygate, the 1918 Armistice, and the Abdication crisis of 1936.