Biology Genetics

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

She Has Her Mother's Laugh presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it.

In this myth-busting book, Daniel Lieberman, professor of human evolutionary biology at Harvard University and a pioneering researcher on the evolution of human physical activity, tells the story of how we never evolved to exercise - to do voluntary physical activity for the sake of health. Using his own research and experiences throughout the world, Lieberman recounts without jargon how and why humans evolved to walk, run, dig, and do other necessary and rewarding physical activities while avoiding needless exertion.

This adventure in science and imagination, which the Medical Tribune said might herald "a Copernican revolution for the life sciences", leads the listener through unexplored jungles and uncharted aspects of mind to the heart of knowledge. In a first-person narrative of scientific discovery that opens new perspectives on biology, anthropology, and the limits of rationalism, The Cosmic Serpent reveals how startlingly different the world around us appears when we open our minds to it.

The Ancestor's Tale is a pilgrimage back through time - a journey on which we meet up with fellow pilgrims as we and they converge on our common ancestors. Chimpanzees join us at about six million years in the past, gorillas at seven million years, orangutans at 14 million years, as we stride on together, a growing band. The journey provides the setting for a collection of some 40 tales.

Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it - a French convent girl who found herself changing sex at puberty; children who, echoing Homer's Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity.

In all animals, mating is a deal. But few creatures behave as if sex is a simple, even mutually beneficial, transaction. Many more treat it with reverence, suspicion, angst, and violence. In the case of the Black Grouse, the bird at the center of Matt Ridley’s investigation, the males dance and sing for hours a day, for several exhausting months, in an arduous and even deadly ritual called a “lek.” To prepare for the ordeal, they grow, preen and display fancy, twisted, bold-colored feathers. When achieved, consummation with a female takes seconds.

The Greatest Show on Earth is a stunning counterattack on advocates of "Intelligent Design," explaining the evidence for evolution while exposing the absurdities of the creationist "argument". Dawkins sifts through rich layers of scientific evidence: from living examples of natural selection to clues in the fossil record; from natural clocks that mark the vast epochs wherein evolution ran its course to the intricacies of developing embryos; from plate tectonics to molecular genetics.

The world is in crisis! What is the solution? Ultimately, we have to find the redeeming, and thus transforming, understanding of our psychologically troubled human condition. And it is precisely that dreamed-of insight, and its now desperately needed transformation of our lives, that Australian biologist Jeremy Griffith presents in this book.

With rapid advances in genomic technologies, genetic testing has become a key part of both clinical practice and research. Scientists are constantly discovering more about how genetics plays a role in health and disease, and healthcare providers are using this information to more accurately identify their patients' particular medical needs. Genetic information is also increasingly being used for a wide range of non-clinical purposes, such as exploring one's ancestry.

Over billions of years, ancient fish evolved to walk on land, reptiles transformed into birds that fly, and apelike primates evolved into humans that walk on two legs, talk, and write. For more than a century, paleontologists have traveled the globe to find fossils that show how such changes have happened.

When Charles Darwin finished The Origin of Species, he thought that he had explained every clue but one. Though his theory could explain many facts, Darwin knew that there was a significant event in the history of life that his theory did not explain. During this event, the "Cambrian explosion", many animals suddenly appeared in the fossil record without apparent ancestors in earlier layers of rock. In Darwin's Doubt, Stephen C. Meyer tells the story of the mystery surrounding this explosion of animal life.

Synthetic biology promises to reveal how life is created and how it can be re-created, enabling scientists to rewrite the rules of our reality. It could help us, for example, heal without prescription medications, grow meat without harvesting animals, or confront our looming climate catastrophe. Synthetic biology will determine the ways in which we conceive future generations and how we define family, how we identify disease and treat aging, where we make our homes, and how we nourish ourselves.

Referring to Lewis Carroll's Red Queen from Through the Looking-Glass, a character who has to keep running to stay in the same place, Matt Ridley demonstrates why sex is humanity's best strategy for outwitting its constantly mutating internal predators.

Why is the world the way it is? How did we get here? Does everything happen for a reason, or are some things left to chance? Philosophers and theologians have pondered these questions for millennia, but startling scientific discoveries over the past half century are revealing that we live in a world driven by chance. A Series of Fortunate Events tells the story of the awesome power of chance and how it is the surprising source of all the beauty and diversity in the living world.

Riley Black brings us back in time to prehistoric seas, swamps, forests, and savannas where critical moments in plant evolution unfolded. Each chapter stars plants and animals alike, underscoring how the interactions between species have helped shape the world we call home. As the chapters move upwards in time, Black guides listeners along the burgeoning trunk of the Tree of Life, stopping to appreciate branches of an evolutionary story that links the world we know with one we can only just perceive now through the silent stone, from ancient roots to the present.

The renowned biologist Paul Nurse has spent his career revealing how living cells work. In What Is Life?, he takes up the challenge of describing what it means to be alive in a way that every listener can understand. It is a shared journey of discovery; step-by-step Nurse illuminates five great ideas that underpin biology - the Cell, the Gene, Evolution by Natural Selection, Life as Chemistry, and Life as Information.

There is no one better qualified than Jared Diamond - renowned expert in the fields of physiology and evolutionary biology and award-winning author - to explain the evolutionary forces that operated on our ancestors to make us sexually different. With wit and a wealth of fascinating examples, he explains how our sexuality has been as crucial as our large brains and upright posture in our rise to human status.

The scientist who has been dubbed the “Father of Intelligent Design” and author of the groundbreaking book Darwin’s Black Box contends that recent scientific discoveries further disprove Darwinism and strengthen the case for an intelligent creator.

In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field is horizontal gene transfer (HGT), or the movement of genes across species lines. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection - a type of HGT. In The Tangled Tree David Quammen chronicles these discoveries through the lives of the researchers who made them.