Genetic Disease

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.

Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.

The DNA Restart, by world-renowned neurogeneticist and New York Times best-selling author Dr. Sharon Moalem, walks you through revolutionary steps to a diet and lifestyle perfect for your individual genetic makeup. The DNA Restart plan utilizes decades of in-depth scientific research into genetics, epigenetics, nutrition, and longevity to explain the pivotal role genes play in the journey to ideal weight and health status.

Experts agree on the value of genetic testing when there is a family history of disease, or if the patient has an illness frequently caused by a mutation. Knowing the disease mutation lets family members find out if they have it too and need preventive care. The book explains that doctors can order tests with genetic counseling at relatively low cost and how this will help them prescribe preventive actions, make earlier diagnoses, and get better outcomes.

Diagnosed with cystic fibrosis at the age of three, Mallory Smith grew up to be a determined, talented young woman who inspired others even as she privately raged against her illness. Despite the daily challenges of endless medical treatments and a deep understanding that she’d never lead a normal life, Mallory was determined to “Live Happy,” a mantra she followed until her death.

Renowned regenerative and restorative sports-medicine doctor Guarav Goswami, MD, provides advanced, minimally invasive (non-surgical) treatments to help his patients get back to peak performance levels - no matter their age. Harnessing the transformative power of stem cells is central to his expertise. In fact, stem cell therapy is proven to be effective in the treatment of many common conditions from arthritis and back pain to Alzheimer’s, Parkinson’s, and cancer. This book is an accessible and informative introduction to the amazing powers of stem cell therapy.

Owen-known to his family as "little buddy" or "Little B"-has a rare genetic disorder that leaves him largely confined to a wheelchair. Before being united with Haatchi, Little B was anxious and found it difficult to make friends. Haatchi-an adorable Anatolian Shepherd puppy-was abused and left for dead on railroad tracks. He was struck by an oncoming train, and although his life was saved, his leg and tail were partially severed. Haatchi was left massively disabled and totally dispirited.

To make this groundbreaking audiobook, Dr. James Lyons-Weiler combed through the past fifty years of published research on autism, exploring subjects such as genetic variation, mechanisms of neurotoxicity of metals and pesticides, and the central and combined roles of each in causing autism.

Jamie Tyrone was 49 years old when she learned she had a 91% chance of getting Alzheimer's disease - by accident through genetic testing. She was shocked, but after an initial bout with depression she decided to take action rather than concede defeat. Jamie teamed up with Dr. Marwan Sabbagh, a renowned neurologist, and together they created a resource detailing not just Jamie's experience, but expert medical advice for anyone facing the disease.

Cystic fibrosis is a life-altering genetic disorder, but with the right knowledge and tools, it can be better understood and managed. The Complete Guide to Cystic Fibrosis provides a clear, comprehensive overview of the disease, making it an essential resource for patients, caregivers, and healthcare professionals.

This audiobook is your roadmap to personal transformation. Learn where you are weak and how to get strong in all areas of life. Immediately start unlocking energy, finding deep, restorative sleep, and boosting mental clarity to upgrade your quality of life. Follow a customized strategy using simple steps to unlock your genetic potential and maximize your results.

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML).

Around 250,000 people have had their genomes sequenced, and scientists expect that number to rise to one billion by 2025. Professor Steven J. Heine argues that the first thing we will do on receiving our DNA test results is to misinterpret them completely. Despite breathless (often lightly researched) media coverage about newly discovered "cancer" or "divorce" or "IQ" genes, the prospect of a DNA test forecasting how your life is going to turn out is vanishingly small.

Did you know that about 10,000 years ago humans went through a radical change in lifestyle in what is now called the Agricultural Revolution? While this event propelled humans out of the stone age and into civilization it also ultimately catapulted us into our current way of life and into the chronic disease epidemic we have today. Western medicine sees our epidemic of disease as a problem that needs to be suppressed, but our chronic disease epidemic is really a symptom.

Eating disorders are one of the most common but elusive conditions to treat in all of Psychiatry. While current treatments do help some patients with eating disorders, many individuals receive little to no benefit from treatment options, leading to a lifelong struggle with anxiety around eating and body image.

For Magda Newman, normal was a goal—she wanted her son Nathaniel to be able to play on the playground, swim at the beach, enjoy the moments of childhood that are often taken for granted. But Nathaniel's severe Treacher Collins syndrome—a craniofacial condition—meant that other concerns came first. Could he eat without the aid of a gastrointestinal tube? Could he hear? Would he ever be able to breathe effortlessly?

Oncologist and cancer gene hunter Theo Ross delivers the first authoritative go-to for people facing a genetic predisposition for cancer. This book empowers listeners to face their genetic heritage without fear and to make decisions that will keep them and their families healthy.

A plane carrying a Russian biochemist crashes in the Alaskan wilderness with no survivors. A dying billionaire launches a final fight against death amid whispers of a now defunct military bioweapon: Project Snowcap. The world's leading CRISPR virologist, Doctor Elijah Vance, hovers on the edge of a breakthrough that will alter humanity at its most fundamental level.

2000年代初頭、人間の全遺伝情報=ヒトゲノムがついに解読された。その後まもなく、山中伸弥らがiPS細胞(人工多能性幹細胞)の作製に成功。そして今、ジェニファー・ダウドナらが開発した新技術「CRISPR-Cas9」により、人類は「ゲノム編集」の時代を迎えている。自らの設計図を望み通りに書き換えられるようになったとき、人間の条件はどう変わるのか? 科学と倫理のせめぎ合いを圧倒的なストーリーテリングで描く傑作。

19世紀後半にメンデルが発見した遺伝の法則とダーウィンの進化論が出会い、遺伝学は歩み始めた。そして今、人類はゲノム編集の時代を迎えている。遺伝子が握る人類の運命とは？　ピュリッツァー賞受賞の医学者が自らの家系に潜む精神疾患の悲劇を織り交ぜながら、圧倒的なストーリーテリングで紡ぐ遺伝子全史