Genetic History

Charles Darwin’s theories, first published more than 150 years ago, still set the paradigm of how we understand the evolution of life—but scientific advances of recent decades have radically altered that understanding. In fact the currently accepted history of life on Earth is flawed and out of date. Now two pioneering scientists, one already an award-winning popular author, deliver an eye-opening narrative that synthesizes a generation’s worth of insights from new research.

This paradigm-shifting book paints a spirited portrait of a restless people that challenges our established ways of looking at Europe's past. The story is more complex than at first believed, with new evidence suggesting that the European gene pool was stirred vigorously multiple times. Genetic clues are also enhancing our understanding of European mobility in epochs with written records, including the arrival of the Anglo-Saxons, the spread of the Slavs, and the adventures of the Vikings.

Throughout his distinguished and unconventional career, engineer-turned-molecular-biologist Douglas Axe has been asking the questions that much of the scientific community would rather silence. Now, he presents his conclusions in this brave and pioneering book. Axe argues that the key to understanding our origin is the "design intuition" - the innate belief held by all humans that tasks we would need knowledge to accomplish can be accomplished only by someone who has that knowledge.

Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it - a French convent girl who found herself changing sex at puberty; children who, echoing Homer's Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity.

From New York Times bestselling author Sam Kean comes incredible stories of science, history, language, and music, as told by our own DNA. In The Disappearing Spoon, bestselling author Sam Kean unlocked the mysteries of the periodic table. In The Violinist's Thumb, he explores the wonders of the...

In The Invisible History of the Human Race, Christine Kenneally draws on cutting-edge research to reveal how both historical artifacts and DNA tell us where we come from and where we may be going. While some books explore our genetic inheritance and some popular television shows celebrate ancestry, this is the first book to explore how everything from DNA to emotions to names and the stories that form our lives are all part of our human legacy.

The discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Howard Markel skillfully recreates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin - fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s - who becomes a focal point for Markel.

Taking us on an incredible journey across centuries and galaxies, accompanied by his characteristic wit, Professor Luke O’Neill explains how it all began, how it will all end and everything in between. Listeners will benefit from Luke’s insatiable curiosity for life when they dive into this ultimate journey through life and death. Among other fascinating facts, you’ll discover the science behind how we got to be so smart, why sex with a caveman was a good idea, the science of finding love, why we follow religions and how robots will become part of everyday life.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

A giant of archaeology, Colin Renfrew has immeasurably improved our understanding of human history. In this passionately argued work, he offers a concise summary of prehistory - human existence that predates the development of written records - while challenging the very definition of prehistory itself.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

The story of how our ancestors made the first tentative steps towards becoming human, how we lost our fur but gained language, fire and tools, and how we strode out of Africa, invented farming and cities and ultimately created modern civilisation. Where did we come from? Where are we going? Homo sapiens is the most successful, the most widespread and the most influential species ever to walk the Earth.

High in the Canadian Rockies is a small limestone quarry formed 530 million years ago called the Burgess Shale. It holds the remains of an ancient sea where dozens of strange creatures lived—a forgotten corner of evolution preserved in awesome detail. In this book, Stephen Jay Gould explores what the Burgess Shale tells us about evolution and the nature of history.

Edward O. Wilson is one of the world’s preeminent biologists, a Pulitzer Prize winner, and the author of more than 25 books. The defining work in a remarkable career, The Social Conquest of Earth boldly addresses age-old questions (Where did we come from? What are we? Where are we going?) while delving into the biological sources of morality, religion, and the creative arts.

One of America’s top physicians traces the history of risk in medicine—with powerful lessons for today Every medical decision—whether to have chemotherapy, an X-ray, or surgery—is a risk, no matter which way you choose. In You Bet Your Life, physician Paul A. Offit argues that, from...

When Bernd Heinrich decided to write a memoir of his ultramarathon running experience, he realized that the preparation for the race was as important, if not more so, than the race itself. In Why We Run, Heinrich considers the flight endurance of birds, the antelope's running prowess and limitations, and the ultra-endurance of camels to understand how human physiology can or cannot replicate these adaptations. Heinrich offers an original and provocative work combining the rigors of science with the passion of running.

In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field is horizontal gene transfer (HGT), or the movement of genes across species lines. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection - a type of HGT. In The Tangled Tree David Quammen chronicles these discoveries through the lives of the researchers who made them.

Drawing on startling new evidence from the mapping of the genome, an explosive new account of the genetic basis of race and its role in the human story. Human evolution, the consensus view insists, ended in prehistory. Inconveniently, as Nicholas Wade argues in A Troublesome Inheritance, the consensus view cannot be right. And in fact, we know that populations have changed in the past few thousand years - to be lactose tolerant, for example, and to survive at high altitudes.

Who are we? How do scientists define Homo sapiens, and how does our species differ from the extinct hominins that came before us? In this accessible account palaeoarchaeologist Paul Pettitt shows how the latest scientific advances, especially in genetics, are revolutionizing our understanding of human evolution. Pettitt reveals the extraordinary story of how our ancestors adapted to unforgiving and relentlessly changing climates, leading to remarkable innovations in art, technology, and society that we are only now beginning to comprehend.

How four tools enabled humanity to control its destiny What enabled us to go from simple stone tools to smartphones? How did bands of hunter-gatherers evolve into multinational empires? Listeners of Sapiens will say a cognitive revolution - a dramatic evolutionary change that altered our brains, turning primitive humans into modern ones - caused a cultural explosion. In Transcendence, Gaia Vince argues instead that modern humans are the product of a nuanced coevolution of our genes, environment, and culture that goes back into deep time.