Genetic History

Since 2010, it has been possible to determine a person's genetic makeup in a matter of days at an accessible cost for many millions of people. Along with this technological breakthrough there has emerged a movement to use this information to help prospective parents "eliminate preventable genetic disease". As the prospect of systematically excluding the appearance of unwanted mutations in our children comes within reach, David B. Goldstein examines the possible consequences from these types of choices.

Are the ways we look at menopause all wrong? Historian Susan Mattern says yes, and The Slow Moon Climbs reveals just how wrong we have been. Taking listeners from the rainforests of Paraguay to the streets of Tokyo, Mattern draws on historical, scientific, and cultural research to reveal how our perceptions of menopause developed from prehistory to today. For most of human history, people had no word for menopause and did not view it as a medical condition. Rather, in traditional foraging and agrarian societies, it was a transition to another important life stage.

In Born in Africa, Martin Meredith follows the trail of discoveries about human origins made by scientists over the last hundred years, recounting their intense rivalry, personal feuds, and fierce controversies, as well as their feats of skill and endurance. The results have been momentous. Scientists have identified more than 20 species of extinct humans. They have firmly established Africa as the birthplace not only of humankind but also of modern humans.

Genetic engineering, which refers to the direct manipulation of DNA, became a reality in the 1970s. In this audiobook, we take a look at how far the field has come, starting with a revolutionary gene-editing tool called CRISPR that’s taking the research world by storm. We then examine how CRISPR and other approaches are being investigated to treat disease, the fantastic-sounding research being done in synthetic biology, controversial efforts in modifying crops and saving species, as well as the numerous ethical issues raised in these areas.

Taking us on an incredible journey across centuries and galaxies, accompanied by his characteristic wit, Professor Luke O’Neill explains how it all began, how it will all end and everything in between. Listeners will benefit from Luke’s insatiable curiosity for life when they dive into this ultimate journey through life and death. Among other fascinating facts, you’ll discover the science behind how we got to be so smart, why sex with a caveman was a good idea, the science of finding love, why we follow religions and how robots will become part of everyday life.

For more than twenty-five years, paleontologist Stephen Jay Gould wrote a column called "The View of Life" for Natural History magazine. More than thirty entries from that column comprise this collection, which covers topics from dinosaurs to baseball and nearly everything in between related to natural history and evolution.

United States of Japan is set in a gripping alternate history where the Japanese Empire rules over America with huge robots. Is resistance possible in the form of subversive video games? Decades ago, Japan won the Second World War. Americans worship their infallible emperor, and nobody believes that Japan's conduct in the war was anything but exemplary. Nobody, that is, except the George Washingtons, a group of rebels fighting for freedom.

This paradigm-shifting book paints a spirited portrait of a restless people that challenges our established ways of looking at Europe's past. The story is more complex than at first believed, with new evidence suggesting that the European gene pool was stirred vigorously multiple times. Genetic clues are also enhancing our understanding of European mobility in epochs with written records, including the arrival of the Anglo-Saxons, the spread of the Slavs, and the adventures of the Vikings.

Everyone has heard the story of DNA as the story of Watson, Crick, and Rosalind Franklin, but knowing the structure of DNA was only part of a greater struggle to understand life's secrets. Life's Greatest Secret is the story of the discovery and cracking of the genetic code, the thing that ultimately enables a spiraling molecule to give rise to the life that exists all around us. This great scientific breakthrough has had far-reaching consequences for how we understand ourselves and our place in the natural world.

With warmth and compassion, Denworth weaves together past and present, field biology and cutting-edge neuroscience, to show how our bodies and minds are designed to make friends, the process by which social bonds develop, and how a drive for friendship underpins human (and nonhuman) society. With its refreshingly optimistic vision of the evolution of human nature, this book puts friendship at the center of our lives.

A revelatory account of how power, politics, and greed have placed the unfulfilled promise of personalized medicine at the center of American medicine The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our...

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

Best-selling author Brian Fagan brings early humans out of the deep freeze with his trademark mix of erudition, cutting-edge science, and vivid storytelling. Cro-Magnon reveals human society in its infancy, facing enormous environmental challenges - including a rival species of humans, the Neanderthals. For ten millennia, Cro-Magnons lived side by side with Neanderthals, an encounter that Fagan fills with drama.

Why is the genome of a salamander 40 times larger than that of a human? Why does the avocado tree produce a million flowers and only a hundred fruits? Why, in short, is there so much waste in nature? In this lively and wide-ranging meditation on the curious accidents and unexpected detours on the path of life, Daniel Milo argues that we ask these questions because we’ve embraced a faulty conception of how evolution - and human society - really works.

From Archimedes to Einstein, discover the lives and works of the scientists who helped shape the world we live in today. Delve into the lives, inspirations, motivations, and achievements of the greatest scientists in the world and through all time. Explore the stories of more than 85 of the...

The discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Howard Markel skillfully recreates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin - fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s - who becomes a focal point for Markel.

More than any other modern scientists, Stephen Jay Gould has opened up to millions the wonders of evolutionary biology. His genius as an essayist lies in his unmatched ability to use his knowledge of the world, including popular culture, to illuminate the realm of science.

In this provocative history of contemporary debates over evolution, veteran journalist Tom Bethell depicts Darwin's theory as a 19th-century idea past its prime, propped up by logical fallacies, bogus claims, and empirical evidence that is all but disintegrating under an onslaught of new scientific discoveries. Bethell presents a concise yet wide-ranging tour of the flash points of modern evolutionary theory. Bethell's account is enriched by his own personal encounters with of some of our era's leading scientists and thinkers.

The Physics of Life argues that the evolution phenomenon is much broader and older than the evolutionary designs that constitute the biosphere, empowering listeners with a new view of the globe and the future, revealing that the urge to have better ideas has the same physical effect as the urge to have better laws and better government. This is evolution explained loudly but also elegantly, forging a path that flows sustainability.

As the oft-repeated and invariably accurate pearl of wisdom goes, a dog truly is man's best friend. For a long time, people have almost universally loved dogs, and it seems to have been that way for at least tens of thousands of years. When affection is abundantly and consistently expressed, this pure, unspoken, wholesome love is one that is very much requited, and then some. This bond can be demonstrated by the mere existence of pet keepers who unironically refer to themselves as “dog parents,” not merely “dog owners”.