Genetic History

“Get your head out of your phone and stop doomscrolling. Read Let Us Play instead.”—Jay Onrait, sports anchor “A crucial playbook that athletes and nonathletes alike can use to help make sports an inclusive place for all.”—Meghan Duggan, 3-time Olympian and Olympic gold medalist, USA...

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

Taking us on an incredible journey across centuries and galaxies, accompanied by his characteristic wit, Professor Luke O’Neill explains how it all began, how it will all end and everything in between. Listeners will benefit from Luke’s insatiable curiosity for life when they dive into this ultimate journey through life and death. Among other fascinating facts, you’ll discover the science behind how we got to be so smart, why sex with a caveman was a good idea, the science of finding love, why we follow religions and how robots will become part of everyday life.

One of America’s top physicians traces the history of risk in medicine—with powerful lessons for today Every medical decision—whether to have chemotherapy, an X-ray, or surgery—is a risk, no matter which way you choose. In You Bet Your Life, physician Paul A. Offit argues that, from the...

Are humans unwitting partners in evolution with psychedelic plants? Darwin’s Pharmacy shows they are by weaving the evolutionary theory of sexual selection and the study of rhetoric together with the science and literature of psychedelic drugs. Long suppressed as components of the human tool kit, psychedelic plants can be usefully modeled as “eloquence adjuncts” that intensify a crucial component of sexual selection in humans: discourse.

In Origin Story, medical historian Howard Markel recounts the two-year period (1858 to 1860) of Darwin's writing of On the Origin of Species through its spectacular success and controversy. Simultaneously, Markel delves into the mysterious health symptoms Darwin developed, combing the literature to emerge with a cogent diagnosis of a case that has long fascinated medical historians.

Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it - a French convent girl who found herself changing sex at puberty; children who, echoing Homer's Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity.

Nicolelis undertakes the first attempt to explain the entirety of human history, culture, and civilization based on a series of recently uncovered key principles of brain function. This new cosmology is centered around three fundamental properties of the human brain: its insurmountable malleability to adapt and learn; its exquisite ability to allow multiple individuals to synchronize their minds around a task, goal, or belief; and its incomparable capacity for abstraction.

United States of Japan is set in a gripping alternate history where the Japanese Empire rules over America with huge robots. Is resistance possible in the form of subversive video games? Decades ago, Japan won the Second World War. Americans worship their infallible emperor, and nobody believes that Japan's conduct in the war was anything but exemplary. Nobody, that is, except the George Washingtons, a group of rebels fighting for freedom.

More than any other modern scientists, Stephen Jay Gould has opened up to millions the wonders of evolutionary biology. His genius as an essayist lies in his unmatched ability to use his knowledge of the world, including popular culture, to illuminate the realm of science.

How four tools enabled humanity to control its destiny What enabled us to go from simple stone tools to smartphones? How did bands of hunter-gatherers evolve into multinational empires? Listeners of Sapiens will say a cognitive revolution - a dramatic evolutionary change that altered our brains, turning primitive humans into modern ones - caused a cultural explosion. In Transcendence, Gaia Vince argues instead that modern humans are the product of a nuanced coevolution of our genes, environment, and culture that goes back into deep time.

Tucked away in Siberia, there are furry, four-legged creatures with wagging tails and floppy ears that are as docile and friendly as any lapdog. But, despite appearances, these are not dogs - they are foxes. They are the result of the most astonishing experiment in breeding ever undertaken - imagine speeding up thousands of years of evolution into a few decades. In 1959, biologists Dmitri Belyaev and Lyudmila Trut set out to do just that, by starting with a few dozen silver foxes from fox farms in the USSR and attempting to recreate the evolution of wolves into dogs in real time.

With warmth and compassion, Denworth weaves together past and present, field biology and cutting-edge neuroscience, to show how our bodies and minds are designed to make friends, the process by which social bonds develop, and how a drive for friendship underpins human (and nonhuman) society. With its refreshingly optimistic vision of the evolution of human nature, this book puts friendship at the center of our lives.

Genetic engineering, which refers to the direct manipulation of DNA, became a reality in the 1970s. In this audiobook, we take a look at how far the field has come, starting with a revolutionary gene-editing tool called CRISPR that’s taking the research world by storm. We then examine how CRISPR and other approaches are being investigated to treat disease, the fantastic-sounding research being done in synthetic biology, controversial efforts in modifying crops and saving species, as well as the numerous ethical issues raised in these areas.

Hace 13.000 años la evolución de las distintas sociedades humanas comenzó a tomar rumbos diferentes. La temprana domesticación de animales y el cultivo de plantas silvestres en el Creciente Fértil, China, Mesoamérica y otras zonas geográficas otorgó una ventaja inicial a sus habitantes. Sin embargo, los orígenes localizados de la agricultura y la ganadería son solo una parte de la explicación de los diferentes destinos. Las sociedades que superaron esta fase de cazadores-recolectores se encontraron con más probabilidades de desarrollo, supervivencia y poder bélico.

From the big bang to the origin and evolution of intelligent life in a search for the meaning of human existence, Why Are We Here?, by author Bruce Brodie, offers a look at evolution and the future of life on the planet.

Few would question that humankind is the crowning achievement of evolution—that history yields progress over time from the primitive and simple to the more advanced and complex—or that identifying an existing trend can be helpful in making important life decisions. We have always identified trends as bad or good. But Stephen Jay Gould argues that this mode of interpretation is a bias that needs correcting.

Fifty thousand years ago - merely a blip in evolutionary time - our Homo sapiens ancestors were competing for existence with several other human species, just as their precursors had done for millions of years. Yet something about our species distinguished it from the pack, and ultimately led to its survival while the rest became extinct. Just what was it that allowed Homo sapiens to become masters of the planet? Ian Tattersall, curator emeritus at the American Museum of Natural History, takes us deep into the fossil record to uncover what made humans so special.

Since 2010, it has been possible to determine a person's genetic makeup in a matter of days at an accessible cost for many millions of people. Along with this technological breakthrough there has emerged a movement to use this information to help prospective parents "eliminate preventable genetic disease". As the prospect of systematically excluding the appearance of unwanted mutations in our children comes within reach, David B. Goldstein examines the possible consequences from these types of choices.

A giant of archaeology, Colin Renfrew has immeasurably improved our understanding of human history. In this passionately argued work, he offers a concise summary of prehistory - human existence that predates the development of written records - while challenging the very definition of prehistory itself.