History Medicine Science

In the early 1960s, Dr. Frances Oldham Kelsey of the U.S. Food and Drug Administration became one of the most celebrated women in America when she prevented a deadly sedative from entering the U.S. market. A Canadian-born pharmacologist and physician, Kelsey saved countless Americans from the devastating side effects of thalidomide, routinely given to pregnant women to prevent morning sickness. As the FDA medical officer charged with reviewing Merrell Pharmaceutical’s application for approval, Kelsey was unconvinced that there was sufficient evidence of the drug’s efficacy and safety.

Alles begann mit einer Doktorarbeit und der Entdeckung des medizinischen Potenzials des Botenmoleküls messenger RNA. Am Ende stehen prominente Investoren wie Dietmar Hopp oder die Gates-Stiftung, Hunderte Millionen staatlicher Finanzierung, der Aufstieg zum Börsenstar und zum erfolgreichen Impfstoffentwickler. Dazwischen liegt ein steiniger Weg auf der Suche nach Unterstützung. Biotech-Unternehmer Wolfgang Klein hat die Anfangszeit als Finanzchef von CureVac selbst miterlebt. Er erzählt die einzigartige und anekdotenreiche Geschichte auf dem Weg zum Weltunternehmen.

Bart Stupak, a nine-term Democratic Congressman from Michigan’s First Congressional District, brought two unshakable principles with him to Capitol Hill in 1992: a firm belief in the sanctity of life, and the conviction that health care was a right for all Americans and not a privilege for the fortunate few. Studies indicating that 45,000 Americans died needlessly every year for lack of access to health care inspired Congressman Stupak’s tireless efforts, often at great personal cost, to pass lifesaving legislation while remaining true to his right-to-life principles.

Decades of data cannot be ignored: African-American adults are far more likely to develop Type 2 diabetes than white adults. In a rousing indictment of the idea that notions of biological race should drive scientific inquiry, Sweetness in the Blood provides an ethnographic picture of biotechnology's framings of Type 2 diabetes risk and race and, importantly, offers a critical examination of the assumptions behind the recruitment of African American and African-descent populations for Type 2 diabetes research.

When Dr. David Hosack tilled the country's first botanical garden in the Manhattan soil more than 200 years ago, he didn't just dramatically alter the New York landscape; he left a monumental legacy of advocacy for public health and wide-ranging support for the sciences. In melodic prose, historian Victoria Johnson eloquently chronicles Hosack's tireless career to reveal the breadth of his impact. The result is a lush portrait of the man who gave voice to a new, deeply American understanding of the powers and perils of nature.

Mysterious and misunderstood, distorted by biblical imagery of disfigurement and uncleanness, Hansen's disease or leprosy has all but disappeared from America's consciousness. In Carville, Louisiana, the closed doors of the nation's last center for the treatment of leprosy open to reveal stories of sadness, separation, and even strength in the face of what was once a life-wrenching diagnosis. Drawn from interviews with living patients and extensive research in the leprosarium's archives, Carville: Remembering Leprosy in America tells the stories of former patients.

Government, industry, and the medical profession, however, have a mixed record when it comes to framing policies and generating knowledge to address drug use and misuse. In Strange Trips, Lucas Richert investigates the myths, meanings, and boundaries of recreational drugs, palliative care drugs, and pharmaceuticals as well as struggles over product innovation, consumer protection, and freedom of choice in the medical marketplace.

The Tragedy of American Science explores how the US economy’s addiction to military spending distorts and deforms science by making it overwhelmingly subservient to military interests. The primary motive driving American science and technology has become the search for new and more efficient ways to kill people. This transforms science from the classic ideal of a creative force for the advancement of humankind into its destructive and antihuman opposite.

Ever since we started huddling together in communities, the story of human history has been inextricably entwined with the story of microbes. They have evolved and spread amongst us, shaping our culture through infection, disease, and pandemic. At the same time, our changing human culture has itself influenced the evolutionary path of microbes. Dorothy H. Crawford here shows that one cannot be truly understood without the other. Beginning with a dramatic account of the SARS pandemic at the start of the 21st century, she takes us back in time to follow the interlinked history of microbes and man....

In this landmark medical narrative, Pulitzer Prize-winning journalists Mark Johnson and Kathleen Gallagher chronicle the story of Nic Volker, the Wisconsin boy at the center of a daring breakthrough in medicine - a complete gene sequencing to discover the cure for an otherwise undiagnosable illness.

On November 23, 1849, in the heart of Boston, one of the city's richest men vanished. Dr. George Parkman, a Brahmin who owned much of Boston's West End, was last seen that afternoon visiting his alma mater, Harvard Medical School. Police scoured city tenements and the harbor - some leads put Parkman at sea or in Manhattan - but a Harvard janitor held a much darker suspicion: that their ruthless benefactor had never even left the Medical School building. His shocking discovery engulfed America in one of its most infamous trials.

Blood Runs Coal comes at a time of resurgent labor movements in the United States and the current administration's attempts to bolster the fossil-fuel industry. Brilliantly researched and compellingly written, it sheds light on the far-reaching effects of industrial and socioeconomic change that unfold across America to this day.

Johns Hopkins University, one of the preeminent medical schools in the nation today, has played a unique role in the history of medicine. When it first opened its doors in 1893, medicine was a rough-and-ready trade. It would soon evolve into a rigorous science. In recent years, medical science has mapped the human genome, deployed robotic tools to perform delicate surgeries, and developed effective vaccines against a host of deadly pathogens. But this transformation could not have happened without the game-changing vision, talent, and dedication of a small cadre of individuals.

If you have ever worn a mask against your better judgement, this book is for you. Delve into the science, psychology, and philosophy involved in the worldwide mania for face coverings. Accessible yet profoundly detailed, packed with meticulously gathered information from a diverse range of disciplines, this book earns its place as an invaluable reference in your library. Its wealth of knowledge equips you to challenge prevailing narratives and verify claims independently.

In 1900, the U.S. sent three doctors to Cuba to discover how yellow fever was spread. There, they launched one of history's most controversial human studies. Compelling and terrifying, The American Plague depicts the story of yellow fever and its reign in this country - and in Africa, where even today it strikes thousands every year. With "arresting tales of heroism," it is a story as much about the nature of human beings as it is about the nature of disease.

In Good Blood, best-selling writer Julian Guthrie tells the gripping tale of the race to cure a horrible affliction known as Rh disease that stalked families and caused a mother’s immune system to attack her own unborn child. The story is anchored by two very different men on two continents: Dr. John Gorman in New York, who would land on a brilliant yet contrarian idea, and the unassuming Australian whose almost magical blood - and his unyielding devotion to donating it - would save millions of lives.

Against a global backdrop of wartime suffering and postwar hope, Borrowing Life gathers the personal histories of the men and women behind the team that enabled and performed the modern medical miracle of the world's first successful organ transplant.

For most of human history, mental illness has been largely untreatable. Sufferers lived their lives - if they survived - in and out of asylums, accumulating life's wreckage around them. In 1948, all that changed when an Australian doctor and recently returned prisoner of war, working alone in a disused kitchen, set about an experimental treatment for one of the scourges of mankind - manic depression, or bipolar disorder. That doctor was John Cade and in that small kitchen he stirred up a miracle.

In 1999, Munjed Al Muderis was a surgical resident working in Baghdad when the military police marched into the operating theatre and ordered the team to mutilate army deserters. When the head of surgery refused, he was executed. Munjed's choices were stark - comply and breach the medical oath, refuse and face death or flee. That day, Munjed's life changed forever. He escaped to Indonesia and boarded a boat to Australia.

Rabies enjoys a fearsome and lurid reputation. Throughout the decades of spiraling growth that defined New York City from the 1840s to the 1910s, the bone-chilling cry of "Mad dog!" possessed the power to upend the ordinary routines and rhythms of urban life. In Mad Dogs and Other New Yorkers, Jessica Wang examines the history of this rare but dreaded affliction during a time of rapid urbanization.