History Medicine Science

In the winter of 1918, at the height of World War I, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in 24 weeks than AIDS has killed in 24 years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision between modern science and epidemic disease.

Can yoga and meditation unleash our inherent supernormal mental powers, such as telepathy, clairvoyance, and precognition? Is it really possible to perceive another person's thoughts and intentions? Influence objects with our minds? Envision future events? And is it possible that some of the superpowers described in ancient legends, science fiction, and comic books are actually real, and patiently waiting for us behind the scenes? Are we now poised for an evolutionary trigger to pull the switch and release our full potentials?

The first major bioterror event in the United States - the anthrax attacks in October 2001 - was a clarion call for scientists who work with "hot" agents to find ways of protecting civilian populations against biological weapons. In The Demon in the Freezer, his first nonfiction book since The Hot Zone, a number-one New York Times best seller, Richard Preston takes us into the heart of USAMRIID, the United States Army Medical Research Institute of Infectious Diseases at Fort Detrick, Maryland.

When three-month-old Lia Lee arrived at the county hospital emergency room in Merced, California, a chain of events was set in motion from which neither she nor her parents nor her doctors would ever recover. Lia's parents, Foua and Nao Kao, were part of a large Hmong community in Merced, refugees from the CIA-run "Quiet War" in Laos.

The story of poison is the story of power. For centuries, royal families have feared the gut-roiling, vomit-inducing agony of a little something added to their food or wine by an enemy. To avoid poison, they depended on tasters, unicorn horns, and antidotes tested on condemned prisoners. Servants licked the royal family's spoons, tried on their underpants, and tested their chamber pots. Ironically, royals terrified of poison were unknowingly poisoning themselves daily with their cosmetics, medications, and filthy living conditions.

For 200 years, a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. What these strange conditions share is their cause: prions.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

Early studies of the human brain used a simple method: Wait for misfortune to strike - strokes, seizures, infectious diseases, horrendous accidents - and see how victims coped. In many cases their survival was miraculous, if puzzling. Observers were amazed by the transformations that took place when different parts of the brain were destroyed, altering victims' personalities. With the lucid, masterful explanations and razor-sharp wit his fans have come to expect, Kean explores the brain's secret passageways.

In Medical Bondage, Cooper Owens examines a wide range of scientific literature and less formal communications in which gynecologists created and disseminated medical fictions about their patients, such as their belief that black enslaved women could withstand pain better than white "ladies". Even as they were advancing medicine, these doctors were legitimizing, for decades to come, groundless theories related to whiteness and blackness, men and women, and the inferiority of other races or nationalities.

In this partially autobiographical work, best-selling author Lewis Thomas offers insights on subjects as wide-ranging as gender differences, how it feels to be a patient, human vs. computer intelligence, the future of cancer research, and the longevity of the planet—interspersing all with charming anecdotes about his family, his colleagues and himself.

In The Poisoner's Handbook, Blum draws from highly original research to track the fascinating, perilous days when a pair of forensic scientists began their trailblazing chemical detective work, fighting to end an era when untraceable poisons offered an easy path to the perfect crime.

Transcribed from the original lectures recorded at San Francisco State University in 1987, The Nature of Drugs series highlights Shulgin’s engaging lecture style peppered with illuminating anecdotes and amusing asides. Ostensibly taught as an introductory course on drugs and biochemistry, these books serve as both a historical record of Shulgin’s teaching style and the culmination of his philosophy on drugs, psychopharmacology, states of consciousness, and societal and individual freedoms pertaining to their use, both medicinal and exploratory.

Pandora's Lab takes us from opium's heyday as the pain reliever of choice to recognition of opioids as a major cause of death in the United States; from the rise of trans fats as the golden ingredient for tastier, cheaper food to the heart disease epidemic that followed; and from the cries to ban DDT for the sake of the environment to an epidemic-level rise in world malaria.

During the height of the COVID-19 pandemic, one renowned scientist, in his famous bowtie, appeared daily on major news networks such as MSNBC, NPR, the BBC, and others. Dr. Peter J. Hotez often went without sleep, working around the clock to develop a nonprofit COVID-19 vaccine and to keep the public informed. During that time, he was one of the most trusted voices on the pandemic and was even nominated for a Nobel Peace Prize for his selfless work. He also became one of the main targets of anti-science rhetoric that gained traction through conservative news media.

What does the history of science reveal about sex and sexuality? Explore the relationship between body and sexual identity with a Harvard-educated expert.

The Nobel laureate Otto Warburg was widely regarded in his day as one of the most important biochemists of the 20th century, a man whose research was integral to humanity’s understanding of cancer. He was also among the most despised figures in Nazi Germany. As a Jewish homosexual living openly with his male partner, Warburg represented all that the Third Reich abhorred. Yet Hitler and his top advisors dreaded cancer, and protected Warburg in the hope that he could cure it.

James A. Garfield may have been the most extraordinary man ever elected president. Born into abject poverty, he rose to become a wunderkind scholar, a Civil War hero, and a renowned and admired reformist congressman. Nominated for president against his will, he engaged in a fierce battle with the corrupt political establishment. But four months after his inauguration, a deranged office seeker tracked Garfield down and shot him in the back. But the shot didn’t kill Garfield. The drama of what hap­pened subsequently is a powerful story of a nation in tur­moil.

Here is P. T. Barnum's insightful review of humbugs, scams, deceits (and self-deceits) in culture, economics, entertainment, religion, medicine, and more.

At the University of Wisconsin, Dr. Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.

With its signature "DARE to keep kids off drugs" slogan and iconic t-shirts, DARE (Drug Abuse Resistance Education) was the most popular drug education program of the 1980s and 1990s. But behind the cultural phenomenon is the story of how DARE and other antidrug education programs brought the War on Drugs into schools and ensured that the velvet glove of antidrug education would be backed by the iron fist of rigorous policing and harsh sentencing.